Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study
Objective: To evaluate the effects of different treatment methods for previous ectopic pregnancies (EP) on cryopreserved embryo transfer (CET) outcomes. Materials and Methods: This was a retrospective cohort study. Patients with EP histories were divided into four groups based on their previous EP t...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-08-01
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| Series: | Gynecology and Minimally Invasive Therapy |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213307017300059 |
| _version_ | 1818317902270431232 |
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| author | Bingqian Zhang Lianbao Cao Lingling Ding Lei Yan Zi-Jiang Chen |
| author_facet | Bingqian Zhang Lianbao Cao Lingling Ding Lei Yan Zi-Jiang Chen |
| author_sort | Bingqian Zhang |
| collection | DOAJ |
| description | Objective: To evaluate the effects of different treatment methods for previous ectopic pregnancies (EP) on cryopreserved embryo transfer (CET) outcomes.
Materials and Methods: This was a retrospective cohort study. Patients with EP histories were divided into four groups based on their previous EP treatments: Group 1—unilateral tubal removal; Group 2—bilateral tubal removal or unilateral tubal removal with contralateral tubal ligation; Group 3—conservative surgery group; and Group 4—conservative medication group. A total of 1333 women with previous histories of being admitted to the hospital for CET treatment were consecutively enrolled between January 2009 and December 2014.
Results: Patients who underwent bilateral tubal ligation or removal had a lower miscarriage rate [8.88% vs. 3.46%, p=0.006, odds ratio=2.718, 95% confidence interval (CI)=1.301–5.677] than those who underwent unilateral tubal removal. No significant difference was observed in the rate of EP after CET in the four groups in women with EP histories. (p1=0.258, 95%CI=0.113–1.836; p2=0.137, 95%CI=0.975–0.997; p3=0.314, 95%CI=0.987–1.001; p4=0.198, 95%CI=0.987–1.001). The groups were not different with regard to other pregnancy outcomes.
Conclusion: There was no significant difference among EP treatment methods with regard to their impacts on CET outcomes in women with EP histories. Bilateral tubal ligation or removal surgery can decrease the miscarriage rate after CET. |
| first_indexed | 2024-12-13T09:44:42Z |
| format | Article |
| id | doaj.art-00516cfaebce4ee3bf9a0822045ee8ab |
| institution | Directory Open Access Journal |
| issn | 2213-3070 |
| language | English |
| last_indexed | 2024-12-13T09:44:42Z |
| publishDate | 2017-08-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Gynecology and Minimally Invasive Therapy |
| spelling | doaj.art-00516cfaebce4ee3bf9a0822045ee8ab2022-12-21T23:52:05ZengWolters Kluwer Medknow PublicationsGynecology and Minimally Invasive Therapy2213-30702017-08-016310310710.1016/j.gmit.2017.01.001Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort studyBingqian Zhang0Lianbao Cao1Lingling Ding2Lei Yan3Zi-Jiang Chen4Center for Reproductive Medicine, Shandong University, Jinan, ChinaCenter for Reproductive Medicine, Shandong University, Jinan, ChinaCenter for Reproductive Medicine, Shandong University, Jinan, ChinaCenter for Reproductive Medicine, Shandong University, Jinan, ChinaCenter for Reproductive Medicine, Shandong University, Jinan, ChinaObjective: To evaluate the effects of different treatment methods for previous ectopic pregnancies (EP) on cryopreserved embryo transfer (CET) outcomes. Materials and Methods: This was a retrospective cohort study. Patients with EP histories were divided into four groups based on their previous EP treatments: Group 1—unilateral tubal removal; Group 2—bilateral tubal removal or unilateral tubal removal with contralateral tubal ligation; Group 3—conservative surgery group; and Group 4—conservative medication group. A total of 1333 women with previous histories of being admitted to the hospital for CET treatment were consecutively enrolled between January 2009 and December 2014. Results: Patients who underwent bilateral tubal ligation or removal had a lower miscarriage rate [8.88% vs. 3.46%, p=0.006, odds ratio=2.718, 95% confidence interval (CI)=1.301–5.677] than those who underwent unilateral tubal removal. No significant difference was observed in the rate of EP after CET in the four groups in women with EP histories. (p1=0.258, 95%CI=0.113–1.836; p2=0.137, 95%CI=0.975–0.997; p3=0.314, 95%CI=0.987–1.001; p4=0.198, 95%CI=0.987–1.001). The groups were not different with regard to other pregnancy outcomes. Conclusion: There was no significant difference among EP treatment methods with regard to their impacts on CET outcomes in women with EP histories. Bilateral tubal ligation or removal surgery can decrease the miscarriage rate after CET.http://www.sciencedirect.com/science/article/pii/S2213307017300059cohort studycryopreserved embryo transferectopic pregnancyin vitro fertilization |
| spellingShingle | Bingqian Zhang Lianbao Cao Lingling Ding Lei Yan Zi-Jiang Chen Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study Gynecology and Minimally Invasive Therapy cohort study cryopreserved embryo transfer ectopic pregnancy in vitro fertilization |
| title | Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study |
| title_full | Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study |
| title_fullStr | Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study |
| title_full_unstemmed | Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study |
| title_short | Effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes: A retrospective cohort study |
| title_sort | effect of different ectopic pregnancy treatments on cryopreserved embryo transfer outcomes a retrospective cohort study |
| topic | cohort study cryopreserved embryo transfer ectopic pregnancy in vitro fertilization |
| url | http://www.sciencedirect.com/science/article/pii/S2213307017300059 |
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