Racial differences in two measures of trust in biomedical research

AbstractObjective:Lack of trust toward medical research is a major barrier to research participation, particularly among some population groups. Valid measures of trust are needed to develop appropriate interventions. The study purpose was to compare two previously validated scales that measure trus...

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Main Authors: Jennifer Cunningham-Erves, Victoria Villalta-Gil, Kenneth A. Wallston, Alaina P. Boyer, Consuelo H. Wilkins
Format: Article
Language:English
Published: Cambridge University Press 2019-06-01
Series:Journal of Clinical and Translational Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2059866119003789/type/journal_article
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author Jennifer Cunningham-Erves
Victoria Villalta-Gil
Kenneth A. Wallston
Alaina P. Boyer
Consuelo H. Wilkins
author_facet Jennifer Cunningham-Erves
Victoria Villalta-Gil
Kenneth A. Wallston
Alaina P. Boyer
Consuelo H. Wilkins
author_sort Jennifer Cunningham-Erves
collection DOAJ
description AbstractObjective:Lack of trust toward medical research is a major barrier to research participation, particularly among some population groups. Valid measures of trust are needed to develop appropriate interventions. The study purpose was to compare two previously validated scales that measure trust in biomedical research – one developed by Hall et al. (H-TBR; 2006) and the other by Mainous et al. (M-TBR; 2006) – in relation to socio-demographic variables and attitudes toward research. Differences between Black and White respondents were explored.Methods:Two nearly identical surveys – one with H-TBR and the other with M-TBR – were systematically administered to a convenience sample. Internal consistency reliability of each scale was assessed. Associations were computed between scores on each scale with attitudes toward biomedical research and demographic variables (i.e., gender, age, race, and socioeconomic status). The difference between White and Black respondents on each TBR score while controlling for age, education, and race was also investigated.Results:A total of 2020 participants completed the H-TBR survey; 1957 completed the M-TBR survey. Mean item scores for M-TBR were higher (F = 56.05, p < 0.001) among Whites than Blacks. Whites also had higher mean item scores than Blacks on H-TBR (F = 7.09, p < 0.001). Both scales showed a strong association with participants’ perceived barriers to research (ps < 0.001) and significant, positive correlations with interest in research participation (ps < 0.001). Age and household income were positive predictors of TBR scores, but the effects of education differed.Conclusions:Both scales are internally consistent and show associations with attitudes toward research. Whites score higher than Blacks on both TBR scales, even while controlling for age and socioeconomic status.
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spelling doaj.art-005adae1f646426f81a6a0767b777c252023-03-09T12:29:47ZengCambridge University PressJournal of Clinical and Translational Science2059-86612019-06-01311311910.1017/cts.2019.378Racial differences in two measures of trust in biomedical researchJennifer Cunningham-Erves0Victoria Villalta-Gil1Kenneth A. Wallston2Alaina P. Boyer3Consuelo H. Wilkins4Department of Internal Medicine, Meharry Medical College, Nashville, Tennessee, USAMeharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee, USAInstitute for Medicine and Public Health, Vanderbilt University Medical Center, Nashville, Tennessee, USANational Health Care for the Homeless Council, Nashville, Tennessee, USADepartment of Internal Medicine, Meharry Medical College, Nashville, Tennessee, USA Meharry-Vanderbilt Alliance, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Medicine, Division of Geriatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USAAbstractObjective:Lack of trust toward medical research is a major barrier to research participation, particularly among some population groups. Valid measures of trust are needed to develop appropriate interventions. The study purpose was to compare two previously validated scales that measure trust in biomedical research – one developed by Hall et al. (H-TBR; 2006) and the other by Mainous et al. (M-TBR; 2006) – in relation to socio-demographic variables and attitudes toward research. Differences between Black and White respondents were explored.Methods:Two nearly identical surveys – one with H-TBR and the other with M-TBR – were systematically administered to a convenience sample. Internal consistency reliability of each scale was assessed. Associations were computed between scores on each scale with attitudes toward biomedical research and demographic variables (i.e., gender, age, race, and socioeconomic status). The difference between White and Black respondents on each TBR score while controlling for age, education, and race was also investigated.Results:A total of 2020 participants completed the H-TBR survey; 1957 completed the M-TBR survey. Mean item scores for M-TBR were higher (F = 56.05, p < 0.001) among Whites than Blacks. Whites also had higher mean item scores than Blacks on H-TBR (F = 7.09, p < 0.001). Both scales showed a strong association with participants’ perceived barriers to research (ps < 0.001) and significant, positive correlations with interest in research participation (ps < 0.001). Age and household income were positive predictors of TBR scores, but the effects of education differed.Conclusions:Both scales are internally consistent and show associations with attitudes toward research. Whites score higher than Blacks on both TBR scales, even while controlling for age and socioeconomic status.https://www.cambridge.org/core/product/identifier/S2059866119003789/type/journal_articleTrustresearch participationpsychometricsassessmentattitudes toward research
spellingShingle Jennifer Cunningham-Erves
Victoria Villalta-Gil
Kenneth A. Wallston
Alaina P. Boyer
Consuelo H. Wilkins
Racial differences in two measures of trust in biomedical research
Journal of Clinical and Translational Science
Trust
research participation
psychometrics
assessment
attitudes toward research
title Racial differences in two measures of trust in biomedical research
title_full Racial differences in two measures of trust in biomedical research
title_fullStr Racial differences in two measures of trust in biomedical research
title_full_unstemmed Racial differences in two measures of trust in biomedical research
title_short Racial differences in two measures of trust in biomedical research
title_sort racial differences in two measures of trust in biomedical research
topic Trust
research participation
psychometrics
assessment
attitudes toward research
url https://www.cambridge.org/core/product/identifier/S2059866119003789/type/journal_article
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