Resistance to Dopamine Agonists in Pituitary Tumors: Molecular Mechanisms

Resistance to Dopamine Agonists in Pituitary Tumors: Molecular Mechanisms

Pituitary neuroendocrine tumors (PitNET) are commonly benign tumors accounting for 10-25% of intracranial tumors. Prolactin-secreting adenomas represent the most predominant type of all PitNET and for this subtype of tumors, the medical therapy relies on the use of dopamine agonists (DAs). DAs yield...

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Bibliographic Details
Main Authors: Claudia Pivonello, Roberta Patalano, Mariarosaria Negri, Rosa Pirchio, Annamaria Colao, Rosario Pivonello, Renata Simona Auriemma
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Endocrinology
Subjects:
dopamine
dopamine agonist
pituitary tumors
cabergoline
prolactinomas
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.791633/full

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