Role of vitamin D and some immunological markers in polycystic ovarian syndrome.
Polycystic ovarian syndrome (PCOS) is the most widespread endocrine-metabolic disorder in women of reproductive age, which is a very common disorder. The current study aimed to determine the levels of vitamin D and immunological markers like antinuclear antibodies (ANA), anti-double strand DNA...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Salahaddin University-Erbil
2023-10-01
|
| Series: | Zanco Journal of Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://zancojournal.su.edu.krd/index.php/JPAS/article/view/709 |
| _version_ | 1827129073185325056 |
|---|---|
| author | Ashraf Najeeb Kakoo Fikry Ali Qadir |
| author_facet | Ashraf Najeeb Kakoo Fikry Ali Qadir |
| author_sort | Ashraf Najeeb Kakoo |
| collection | DOAJ |
| description |
Polycystic ovarian syndrome (PCOS) is the most widespread endocrine-metabolic disorder in women of reproductive age, which is a very common disorder. The current study aimed to determine the levels of vitamin D and immunological markers like antinuclear antibodies (ANA), anti-double strand DNA (dsDNA) and C. reactive protein (CRP) in the serum of PCOS-affected women. Blood samples were collected from forty polycystic women depending on the Rotterdam criteria. Forty fertile women of similar ages made up the control group. The Blood samples were analyzed to measure the levels of an endocrine hormone and vitamin D by Cobas e411; ANA and ds DNA determined by Enzyme-Linked Immunosorbent Assay ( ELISA), And CRP measured by Cobas C111. This study revealed a significant decrease in vitamin D in PCOS patients contrasted to the control group, while CRP, ANA, and dsDNA increased significantly in PCOS patients. Finding low vitamin D and high ANA, ds DNA in PCOS women may have a role in the aetiology of PCOS. Screening for autoantibodies and vitamin D in women with PCOS may provide better insight into its role in PCOS.
|
| first_indexed | 2024-03-08T11:50:58Z |
| format | Article |
| id | doaj.art-00630536fbd84fd698e76275f6a2c014 |
| institution | Directory Open Access Journal |
| issn | 2218-0230 2412-3986 |
| language | English |
| last_indexed | 2025-03-20T15:54:29Z |
| publishDate | 2023-10-01 |
| publisher | Salahaddin University-Erbil |
| record_format | Article |
| series | Zanco Journal of Pure and Applied Sciences |
| spelling | doaj.art-00630536fbd84fd698e76275f6a2c0142024-09-02T08:56:58ZengSalahaddin University-ErbilZanco Journal of Pure and Applied Sciences2218-02302412-39862023-10-0135510.21271/ZJPAS.35.5.9Role of vitamin D and some immunological markers in polycystic ovarian syndrome.Ashraf Najeeb Kakoo 0Fikry Ali Qadir 1Department of Biology, College of Science, Salahaddin University-Erbil, Kurdistan Region, IraqDepartment of Biology, College of Science, Salahaddin University-Erbil, Kurdistan Region, Iraq Polycystic ovarian syndrome (PCOS) is the most widespread endocrine-metabolic disorder in women of reproductive age, which is a very common disorder. The current study aimed to determine the levels of vitamin D and immunological markers like antinuclear antibodies (ANA), anti-double strand DNA (dsDNA) and C. reactive protein (CRP) in the serum of PCOS-affected women. Blood samples were collected from forty polycystic women depending on the Rotterdam criteria. Forty fertile women of similar ages made up the control group. The Blood samples were analyzed to measure the levels of an endocrine hormone and vitamin D by Cobas e411; ANA and ds DNA determined by Enzyme-Linked Immunosorbent Assay ( ELISA), And CRP measured by Cobas C111. This study revealed a significant decrease in vitamin D in PCOS patients contrasted to the control group, while CRP, ANA, and dsDNA increased significantly in PCOS patients. Finding low vitamin D and high ANA, ds DNA in PCOS women may have a role in the aetiology of PCOS. Screening for autoantibodies and vitamin D in women with PCOS may provide better insight into its role in PCOS. https://zancojournal.su.edu.krd/index.php/JPAS/article/view/709Autoimmune markersC. reactive proteinPolycystic ovary syndromeVitamin D |
| spellingShingle | Ashraf Najeeb Kakoo Fikry Ali Qadir Role of vitamin D and some immunological markers in polycystic ovarian syndrome. Zanco Journal of Pure and Applied Sciences Autoimmune markers C. reactive protein Polycystic ovary syndrome Vitamin D |
| title | Role of vitamin D and some immunological markers in polycystic ovarian syndrome. |
| title_full | Role of vitamin D and some immunological markers in polycystic ovarian syndrome. |
| title_fullStr | Role of vitamin D and some immunological markers in polycystic ovarian syndrome. |
| title_full_unstemmed | Role of vitamin D and some immunological markers in polycystic ovarian syndrome. |
| title_short | Role of vitamin D and some immunological markers in polycystic ovarian syndrome. |
| title_sort | role of vitamin d and some immunological markers in polycystic ovarian syndrome |
| topic | Autoimmune markers C. reactive protein Polycystic ovary syndrome Vitamin D |
| url | https://zancojournal.su.edu.krd/index.php/JPAS/article/view/709 |
| work_keys_str_mv | AT ashrafnajeebkakoo roleofvitamindandsomeimmunologicalmarkersinpolycysticovariansyndrome AT fikryaliqadir roleofvitamindandsomeimmunologicalmarkersinpolycysticovariansyndrome |