Vitamin D3 ameliorates nitrogen mustard‐induced cutaneous inflammation by inactivating the NLRP3 inflammasome through the SIRT3–SOD2–mtROS signaling pathway
Abstract Nitrogen mustard (NM) causes severe skin injury with an obvious inflammatory response, which is lack of effective and targeted therapies. Vitamin D3 (VD3) has excellent anti‐inflammatory properties and is considered as a potential candidate for the treatment of NM‐induced dermal toxicity; h...
Main Authors: | Xunhu Dong, Ying He, Feng Ye, Yuanpeng Zhao, Jin Cheng, Jingsong Xiao, Wenpei Yu, Jiqing Zhao, Yan Sai, Guorong Dan, Mingliang Chen, Zhongmin Zou |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-02-01
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Series: | Clinical and Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/ctm2.312 |
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