Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma
Currently, Kaposi’s sarcoma (KS) is treated following the recommendations of international guidelines. These guidelines recommend esophagogastroduodenoscopy/colonoscopy for detecting multicentric KS of visceral lesions. Second primary malignancies (SPMs) are also a common KS complication; however, i...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/10/4/218 |
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| author | Nobuyuki Maruyama Yuko Okubo Masato Umikawa Akiko Matsuzaki Akira Hokama Fusahiro Hirano Tessho Maruyama Kazuhide Nishihara Toshiyuki Nakasone Shoko Makishi Hiroyuki Nakamura Naoki Yoshimi |
| author_facet | Nobuyuki Maruyama Yuko Okubo Masato Umikawa Akiko Matsuzaki Akira Hokama Fusahiro Hirano Tessho Maruyama Kazuhide Nishihara Toshiyuki Nakasone Shoko Makishi Hiroyuki Nakamura Naoki Yoshimi |
| author_sort | Nobuyuki Maruyama |
| collection | DOAJ |
| description | Currently, Kaposi’s sarcoma (KS) is treated following the recommendations of international guidelines. These guidelines recommend esophagogastroduodenoscopy/colonoscopy for detecting multicentric KS of visceral lesions. Second primary malignancies (SPMs) are also a common KS complication; however, information on their detection and treatment is unfortunately not yet indicated in these guidelines. This paper reports on an 86-year-old man who suffered from quadruple primary malignancies: skin classic KS with colon adenocarcinoma, oral squamous cell carcinoma (maxilla), and well-differentiated stomach adenocarcinoma. Gastric cancer was incidentally detected during esophagogastroduodenoscopy, which was performed to detect visceral KS. We suggest that esophagogastroduodenoscopy/colonoscopy be routinely performed during the follow-up of patients with KS. As SPMs are crucial complications in patients with KS, these malignancies should be detected as early as possible. |
| first_indexed | 2024-03-10T20:28:39Z |
| format | Article |
| id | doaj.art-006a744994b049a2910ac884862fd639 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T20:28:39Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-006a744994b049a2910ac884862fd6392023-11-19T21:33:30ZengMDPI AGDiagnostics2075-44182020-04-0110421810.3390/diagnostics10040218Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s SarcomaNobuyuki Maruyama0Yuko Okubo1Masato Umikawa2Akiko Matsuzaki3Akira Hokama4Fusahiro Hirano5Tessho Maruyama6Kazuhide Nishihara7Toshiyuki Nakasone8Shoko Makishi9Hiroyuki Nakamura10Naoki Yoshimi11Department of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Dermatology, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Medical Biochemistry, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Pathology, Ryukyu University Hospital, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Endoscopy, Ryukyu University Hospital, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Oral and Maxillofacial Surgery, Ryukyu University Hospital, 207 Uehara, Nishihara, Okinawa 903-0215, JapanMolecular Microbiology Group, Tropical Biosphere Research Center, University of the Ryukyus, Senbaru 1, Nishihara, Okinawa 903-0213, JapanDepartment of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Oral and Maxillofacial Surgery, Ryukyu University Hospital, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Oral and Maxillofacial Functional Rehabilitation, Graduate School of Medicine, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215, JapanDepartment of Pathology, Ryukyu University Hospital, 207 Uehara, Nishihara, Okinawa 903-0215, JapanCurrently, Kaposi’s sarcoma (KS) is treated following the recommendations of international guidelines. These guidelines recommend esophagogastroduodenoscopy/colonoscopy for detecting multicentric KS of visceral lesions. Second primary malignancies (SPMs) are also a common KS complication; however, information on their detection and treatment is unfortunately not yet indicated in these guidelines. This paper reports on an 86-year-old man who suffered from quadruple primary malignancies: skin classic KS with colon adenocarcinoma, oral squamous cell carcinoma (maxilla), and well-differentiated stomach adenocarcinoma. Gastric cancer was incidentally detected during esophagogastroduodenoscopy, which was performed to detect visceral KS. We suggest that esophagogastroduodenoscopy/colonoscopy be routinely performed during the follow-up of patients with KS. As SPMs are crucial complications in patients with KS, these malignancies should be detected as early as possible.https://www.mdpi.com/2075-4418/10/4/218kaposi’s sarcomasecond primary malignancyvisceralupper endoscopyesophagogastroduodenoscopycolonoscopy |
| spellingShingle | Nobuyuki Maruyama Yuko Okubo Masato Umikawa Akiko Matsuzaki Akira Hokama Fusahiro Hirano Tessho Maruyama Kazuhide Nishihara Toshiyuki Nakasone Shoko Makishi Hiroyuki Nakamura Naoki Yoshimi Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma Diagnostics kaposi’s sarcoma second primary malignancy visceral upper endoscopy esophagogastroduodenoscopy colonoscopy |
| title | Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma |
| title_full | Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma |
| title_fullStr | Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma |
| title_full_unstemmed | Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma |
| title_short | Quadruple Multiple Primary Malignancies: Early Detection of Second Primary Malignancy by Esophagogastroduodenoscopy/Colonoscopy Is Crucial for Patients with Classic Kaposi’s Sarcoma |
| title_sort | quadruple multiple primary malignancies early detection of second primary malignancy by esophagogastroduodenoscopy colonoscopy is crucial for patients with classic kaposi s sarcoma |
| topic | kaposi’s sarcoma second primary malignancy visceral upper endoscopy esophagogastroduodenoscopy colonoscopy |
| url | https://www.mdpi.com/2075-4418/10/4/218 |
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