On the origin of the Biomphalaria glabrata hemocytes
A histologic, morphometric and ultrastructural study performed on Biomphalaria glabrata submitted to infection with Schistosoma mansoni miracidia failed to provide significant evidences that the so-called amebocyte-producing organ (APO) is really the central organ for hemocyte production. In infecte...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2006-10-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000900033 |
| _version_ | 1797756609513914368 |
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| author | Samaly dos Santos Souza Zilton A Andrade |
| author_facet | Samaly dos Santos Souza Zilton A Andrade |
| author_sort | Samaly dos Santos Souza |
| collection | DOAJ |
| description | A histologic, morphometric and ultrastructural study performed on Biomphalaria glabrata submitted to infection with Schistosoma mansoni miracidia failed to provide significant evidences that the so-called amebocyte-producing organ (APO) is really the central organ for hemocyte production. In infected snails no general reactive changes appeared in the APO, the mitoses were seen only occasionally, and the possibility of cellular hyperplasia was ruled out by morphometric measurements. Under the electron microscope the APO cells presented an essentially epithelial structure, without features indicative of transition toward hemocytes. On the other hand, the present findings pointed to a multicentric origin for the mollusck hemocytes, as earlier studies had indicated. Dense foci of hemocyte collections appeared sometimes around disintegrating sporocysts and cercariae in several organs and tissues of the infected snails, including a curious accumulation of such cells inside the ventricular cavity of the heart. In the heart and other sites, features suggestive of transformation of vascular space endothelial lining cells into hemocytes were apparent. To some extent, the postulated multicentric origin for B. glabrata hemocytes recapitulates earlier embryologic findings in vertebrates, when mesenchymal vascular spaces generate the circulating and phagocytic blood cells. |
| first_indexed | 2024-03-12T18:04:01Z |
| format | Article |
| id | doaj.art-006e7d1852874a4c9c7fcfe095fb44a4 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:04:01Z |
| publishDate | 2006-10-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-006e7d1852874a4c9c7fcfe095fb44a42023-08-02T09:32:17ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602006-10-0110121321810.1590/S0074-02762006000900033On the origin of the Biomphalaria glabrata hemocytesSamaly dos Santos SouzaZilton A AndradeA histologic, morphometric and ultrastructural study performed on Biomphalaria glabrata submitted to infection with Schistosoma mansoni miracidia failed to provide significant evidences that the so-called amebocyte-producing organ (APO) is really the central organ for hemocyte production. In infected snails no general reactive changes appeared in the APO, the mitoses were seen only occasionally, and the possibility of cellular hyperplasia was ruled out by morphometric measurements. Under the electron microscope the APO cells presented an essentially epithelial structure, without features indicative of transition toward hemocytes. On the other hand, the present findings pointed to a multicentric origin for the mollusck hemocytes, as earlier studies had indicated. Dense foci of hemocyte collections appeared sometimes around disintegrating sporocysts and cercariae in several organs and tissues of the infected snails, including a curious accumulation of such cells inside the ventricular cavity of the heart. In the heart and other sites, features suggestive of transformation of vascular space endothelial lining cells into hemocytes were apparent. To some extent, the postulated multicentric origin for B. glabrata hemocytes recapitulates earlier embryologic findings in vertebrates, when mesenchymal vascular spaces generate the circulating and phagocytic blood cells.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000900033amebocyteproducing organhemocytesBiomphalaria glabrataSchistosoma mansoni |
| spellingShingle | Samaly dos Santos Souza Zilton A Andrade On the origin of the Biomphalaria glabrata hemocytes Memorias do Instituto Oswaldo Cruz amebocyte producing organ hemocytes Biomphalaria glabrata Schistosoma mansoni |
| title | On the origin of the Biomphalaria glabrata hemocytes |
| title_full | On the origin of the Biomphalaria glabrata hemocytes |
| title_fullStr | On the origin of the Biomphalaria glabrata hemocytes |
| title_full_unstemmed | On the origin of the Biomphalaria glabrata hemocytes |
| title_short | On the origin of the Biomphalaria glabrata hemocytes |
| title_sort | on the origin of the biomphalaria glabrata hemocytes |
| topic | amebocyte producing organ hemocytes Biomphalaria glabrata Schistosoma mansoni |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000900033 |
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