Peri-implantitis and systemic inflammation: A critical update
Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, inclu...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Saudi Dental Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905223000718 |
| _version_ | 1797776696409063424 |
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| author | Nasser M. Assery Carlos A. Jurado Mansour K. Assery Kelvin I. Afrashtehfar |
| author_facet | Nasser M. Assery Carlos A. Jurado Mansour K. Assery Kelvin I. Afrashtehfar |
| author_sort | Nasser M. Assery |
| collection | DOAJ |
| description | Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, including uncontrolled diabetes mellitus, psychological stress, cardiovascular disease, obesity, and infectious diseases such as COVID-19. As an inflammatory disease, peri-implantitis may trigger systemic inflammation by elevating circulating levels of pro-inflammatory cytokines, which could have unknown impacts on overall health. While the relationship between periodontal health and systemic conditions is better understood, the association between peri-implant disease and systemic inflammation remains unclear. Therefore, this comprehensive review aims to summarize the most recent evidence on the relationship between peri-implantitis and systemic inflammation, focusing on biological complications, microbiology, and biomarkers. This review aims to enhance our understanding of the links between peri-implantitis and systemic inflammation and promote further research in this field by discussing the latest insights and clinical implications. |
| first_indexed | 2024-03-12T22:53:35Z |
| format | Article |
| id | doaj.art-0071fdd4e11b40e9a7dfe1b240e0fe51 |
| institution | Directory Open Access Journal |
| issn | 1013-9052 |
| language | English |
| last_indexed | 2024-03-12T22:53:35Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj.art-0071fdd4e11b40e9a7dfe1b240e0fe512023-07-20T04:37:35ZengElsevierSaudi Dental Journal1013-90522023-07-01355443450Peri-implantitis and systemic inflammation: A critical updateNasser M. Assery0Carlos A. Jurado1Mansour K. Assery2Kelvin I. Afrashtehfar3Department of Periodontology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY 14642, USADepartment of Prosthodontics, School of Dentistry, Iowa University, Iowa City, IA 52242, USACollege of Dentistry, Riyadh Elm University, Riyadh 13244, Saudi ArabiaEvidence-Based Practice Unit (EBPU), Clinical Sciences Department, College of Dentistry, Ajman University, PO Box 346, Ajman City, AE, United Arab Emirates; Department of Reconstructive Dentistry & Gerodontology, School of Dental Medicine, Faculty of Medicine, University of Bern, 3010 Berne, BE, Switzerland; Division of Periodontology and Peri-implant Diseases, Center of Dental Medicine, University of Zurich, 8032 Zurich, ZH, Switzerland; Artificial Intelligence Research Center (AIRC), Ajman City, P.O. Box 346, AE, United Arab Emirates; Corresponding author at: Division of Restorative Dental Sciences, College of Dentistry, Ajman University, PO Box 346, Ajman City, Ajman Emirate, United Arab Emirates.Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, including uncontrolled diabetes mellitus, psychological stress, cardiovascular disease, obesity, and infectious diseases such as COVID-19. As an inflammatory disease, peri-implantitis may trigger systemic inflammation by elevating circulating levels of pro-inflammatory cytokines, which could have unknown impacts on overall health. While the relationship between periodontal health and systemic conditions is better understood, the association between peri-implant disease and systemic inflammation remains unclear. Therefore, this comprehensive review aims to summarize the most recent evidence on the relationship between peri-implantitis and systemic inflammation, focusing on biological complications, microbiology, and biomarkers. This review aims to enhance our understanding of the links between peri-implantitis and systemic inflammation and promote further research in this field by discussing the latest insights and clinical implications.http://www.sciencedirect.com/science/article/pii/S1013905223000718Biological complicationsBiomarkersCardiovascular diseaseDental implantsInflammationMicrobiology |
| spellingShingle | Nasser M. Assery Carlos A. Jurado Mansour K. Assery Kelvin I. Afrashtehfar Peri-implantitis and systemic inflammation: A critical update Saudi Dental Journal Biological complications Biomarkers Cardiovascular disease Dental implants Inflammation Microbiology |
| title | Peri-implantitis and systemic inflammation: A critical update |
| title_full | Peri-implantitis and systemic inflammation: A critical update |
| title_fullStr | Peri-implantitis and systemic inflammation: A critical update |
| title_full_unstemmed | Peri-implantitis and systemic inflammation: A critical update |
| title_short | Peri-implantitis and systemic inflammation: A critical update |
| title_sort | peri implantitis and systemic inflammation a critical update |
| topic | Biological complications Biomarkers Cardiovascular disease Dental implants Inflammation Microbiology |
| url | http://www.sciencedirect.com/science/article/pii/S1013905223000718 |
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