Melatonin treatment reduces astrogliosis and apoptosis in rats with traumatic brain injury

Melatonin treatment reduces astrogliosis and apoptosis in rats with traumatic brain injury

Objective(s):Melatonin is known as an anti-inflammatory agent, and it has been proven to exert neuroprotection through inhibition of cell death (apoptosis) in several models of brain injury.Secondary injury following the primary traumatic brain injury (TBI) results in glial cells activation, especia...

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Main Authors: Abdolreza Babaee, Seyed Hassan Eftekhar-Vaghefi, Majid Asadi-shekaari, Nader Shahrokhi, Samereh Dehghani Soltani, Reza Malekpour-Afshar, Mohsen Basiri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apoptosis
Astrogliosis
GFAP
Melatonin
Traumatic brain injury
Online Access:http://ijbms.mums.ac.ir/pdf_5207_24b666306a02a7b319c7bcc14e305868.html

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