Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism

Geniposide Ameliorates Liver Fibrosis Through Reducing Oxidative Stress and Inflammatory Respose, Inhibiting Apoptosis and Modulating Overall Metabolism

Liver fibrosis is a progressive liver damage condition caused by various factors and may progress toward liver cirrhosis, and even hepatocellular carcinoma. Many studies have found that the disfunction in metabolism could contribute to the development of liver fibrosis. Geniposide, derived from Gard...

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Bibliographic Details
Main Authors: Lu Yang, Liping Bi, Lulu Jin, Yuming Wang, Yuting Li, Zixuan Li, Wenju He, Huantian Cui, Jing Miao, Li Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Pharmacology
Subjects:
liver fibrosis
geniposide
untargeted metabolomic analysis
oxidative stress
inflammation
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.772635/full

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