Effect of P-glycoprotein Inhibitor (Carvedilol) on Developmental Outcome Methotrexate are Given Alone and in Combination of Pregnant Rats

Effect of P-glycoprotein Inhibitor (Carvedilol) on Developmental Outcome Methotrexate are Given Alone and in Combination of Pregnant Rats

This study was performed according to FDA protocol to evaluate the developmental effects of carvedilol (P-glycoprotein inhibitor), methotrexate (P-glycoprotein substrate) and their combination at therapeutic doses on pregnant rats. Sixty Albino Wistar rats (40 female rats and 20 males) were...

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Bibliographic Details
Main Authors: Zaid K Shnawa, Duraid A Abass
Format: Article
Language:English
Published: University of Baghdad, College of Veterinary Medicine 2022-12-01
Series:The Iraqi Journal of Veterinary Medicine
Subjects:
methotrexate
carvedilol
P-glycoprotein inhibitor
teratogenesis
rat
Online Access:https://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1410

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