Attenuation of CCl4-induced hepatic fibrosis in mice by vaccinating against TGF-β1.
Transforming growth factor β1 (TGF-β1) is the pivotal pro-fibrogenic cytokine in hepatic fibrosis. Reducing the over-produced expression of TGF-β1 or blocking its signaling pathways is considered to be a promising therapeutic strategy for hepatic fibrosis. In this study, we evaluated the feasibility...
| Autores principales: | , , , , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Public Library of Science (PLoS)
2013-01-01
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| Colección: | PLoS ONE |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349218/pdf/?tool=EBI |