H4-methylation regulators mediated epitranscriptome patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma

H4-methylation regulators mediated epitranscriptome patterns and tumor microenvironment infiltration characterization in hepatocellular carcinoma

Abstract Epigenetic modifications are involved in the remodeling of the tumor microenvironment (TME) and the regulation of immune response. Nonetheless, the role of histone H4 methylation (H4M) modification in the TME and immune regulation of hepatocellular carcinoma (HCC) is unknown. As a result, t...

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Bibliographic Details
Main Authors:	Linyuan Yu, Tao Ji, Wei Liao, Yuyan Xu, Yinghao Fang, Qing Zhu, Jianmin Nie, Dinghua Yang
Format:	Article
Language:	English
Published:	BMC 2023-03-01
Series:	Clinical Epigenetics
Subjects:	Histone H4 methylation Hepatocellular carcinoma Molecular subtype Tumor microenvironment Immunotherapy biomarker
Online Access:	https://doi.org/10.1186/s13148-023-01460-6

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