The Roles of Coenzyme A Binding Pocket Residues in Short and Medium Chain Acyl-CoA Synthetases
Short- and medium-chain acyl-CoA synthetases catalyze similar two-step reactions in which acyl substrate and ATP bind to form an enzyme-bound acyl-adenylate, then CoA binds for formation of the acyl-CoA product. We investigated the roles of active site residues in CoA binding in acetyl-CoA synthetas...
| Main Authors: | , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
MDPI AG
2023-07-01
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| 叢編: | Life |
| 主題: | |
| 在線閱讀: | https://www.mdpi.com/2075-1729/13/8/1643 |