Contemporary Surgical Management of Colorectal Liver Metastases
Colorectal cancer is the third most common cancer in the United States and the second most common cause of cancer-related death. Approximately 20–30% of patients will develop hepatic metastasis in the form of synchronous or metachronous disease. The treatment of colorectal liver metastasis (CRLM) ha...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/16/5/941 |
| _version_ | 1797264687388164096 |
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| author | Pratik Chandra Greg D. Sacks |
| author_facet | Pratik Chandra Greg D. Sacks |
| author_sort | Pratik Chandra |
| collection | DOAJ |
| description | Colorectal cancer is the third most common cancer in the United States and the second most common cause of cancer-related death. Approximately 20–30% of patients will develop hepatic metastasis in the form of synchronous or metachronous disease. The treatment of colorectal liver metastasis (CRLM) has evolved into a multidisciplinary approach, with chemotherapy and a variety of locoregional treatments, such as ablation and portal vein embolization, playing a crucial role. However, resection remains a core tenet of management, serving as the gold standard for a curative-intent therapy. As such, the input of a dedicated hepatobiliary surgeon is paramount for appropriate patient selection and choice of surgical approach, as significant advances in the field have made management decisions extremely nuanced and complex. We herein aim to review the contemporary surgical management of colorectal liver metastasis with respect to both perioperative and operative considerations. |
| first_indexed | 2024-04-25T00:32:52Z |
| format | Article |
| id | doaj.art-008464e940c64aec810aa0ce67a2e3dc |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-04-25T00:32:52Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-008464e940c64aec810aa0ce67a2e3dc2024-03-12T16:40:55ZengMDPI AGCancers2072-66942024-02-0116594110.3390/cancers16050941Contemporary Surgical Management of Colorectal Liver MetastasesPratik Chandra0Greg D. Sacks1Department of Surgery, NYU Grossman School of Medicine, New York, NY 10016, USADepartment of Surgery, NYU Grossman School of Medicine, New York, NY 10016, USAColorectal cancer is the third most common cancer in the United States and the second most common cause of cancer-related death. Approximately 20–30% of patients will develop hepatic metastasis in the form of synchronous or metachronous disease. The treatment of colorectal liver metastasis (CRLM) has evolved into a multidisciplinary approach, with chemotherapy and a variety of locoregional treatments, such as ablation and portal vein embolization, playing a crucial role. However, resection remains a core tenet of management, serving as the gold standard for a curative-intent therapy. As such, the input of a dedicated hepatobiliary surgeon is paramount for appropriate patient selection and choice of surgical approach, as significant advances in the field have made management decisions extremely nuanced and complex. We herein aim to review the contemporary surgical management of colorectal liver metastasis with respect to both perioperative and operative considerations.https://www.mdpi.com/2072-6694/16/5/941colorectal liver metastasistreatment sequencingportal vein embolizationresection marginhepatic arterial infusion pumptwo-stage hepatectomy |
| spellingShingle | Pratik Chandra Greg D. Sacks Contemporary Surgical Management of Colorectal Liver Metastases Cancers colorectal liver metastasis treatment sequencing portal vein embolization resection margin hepatic arterial infusion pump two-stage hepatectomy |
| title | Contemporary Surgical Management of Colorectal Liver Metastases |
| title_full | Contemporary Surgical Management of Colorectal Liver Metastases |
| title_fullStr | Contemporary Surgical Management of Colorectal Liver Metastases |
| title_full_unstemmed | Contemporary Surgical Management of Colorectal Liver Metastases |
| title_short | Contemporary Surgical Management of Colorectal Liver Metastases |
| title_sort | contemporary surgical management of colorectal liver metastases |
| topic | colorectal liver metastasis treatment sequencing portal vein embolization resection margin hepatic arterial infusion pump two-stage hepatectomy |
| url | https://www.mdpi.com/2072-6694/16/5/941 |
| work_keys_str_mv | AT pratikchandra contemporarysurgicalmanagementofcolorectallivermetastases AT gregdsacks contemporarysurgicalmanagementofcolorectallivermetastases |