Molecular Dynamics Simulation of T10609C and C10676G Mutations of Mitochondrial Gene Associated With Proton Translocation in Type 2 Diabetes Mellitus and Cataract Patients
The mutation rate of mitochondrial DNA (mtDNA) is 17 times higher than nuclear DNA, and these mutations can cause mitochondrial disease in 1 of 10.000 people. The T10609C mutation was identified in type 2 diabetes mellitus (T2DM) patients and the C10676G mutation in cataract patients, with both muta...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-12-01
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| Series: | Bioinformatics and Biology Insights |
| Online Access: | https://doi.org/10.1177/1177932220978672 |