Acute idiopathic blind spot enlargement syndrome following influenza vaccination
Purpose: To report a case of acute idiopathic blind spot enlargement syndrome (AIBSES) following influenza vaccination. Observations: A 57-year old woman presented with a one-month history of photopsia, temporal visual field disturbance on the right eye, 11 days following the administration of the i...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-12-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993620302644 |
| _version_ | 1819077407053709312 |
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| author | Xavier Quinones, MD Jan Ortiz, MD Carmen Santos, MD Armando L. Oliver, MD Julio Rodríguez, MD |
| author_facet | Xavier Quinones, MD Jan Ortiz, MD Carmen Santos, MD Armando L. Oliver, MD Julio Rodríguez, MD |
| author_sort | Xavier Quinones, MD |
| collection | DOAJ |
| description | Purpose: To report a case of acute idiopathic blind spot enlargement syndrome (AIBSES) following influenza vaccination. Observations: A 57-year old woman presented with a one-month history of photopsia, temporal visual field disturbance on the right eye, 11 days following the administration of the influenza virus vaccine. Visual acuity was 20/30, and color vision remained normal. Examination revealed mild venular dilation at the edge of the right optic disk and was otherwise unremarkable. Visual field testing revealed enlargement of the right physiological blind spot. Medical workup, including brain CT scan, brain MRI, RPR, Treponema pallidum antibodies, Chest X-Ray, ANA, and PPD testing, was found within normal limits. Ancillary testing was compatible with an assessment of AIBSES secondary to influenza virus vaccination. Conclusions and Importance: Although direct causation may not be absolutely established by a single report, our case suggests that the influenza virus vaccine may serve as an immunological trigger for some cases of AIBSES. Thoughtful vaccination history is of the utmost importance when evaluating patients with AIBSES, as it may help elucidate the underlying precipitating factor. To our knowledge, this is the first reported case of AIBSES following influenza virus vaccination. |
| first_indexed | 2024-12-21T18:56:42Z |
| format | Article |
| id | doaj.art-0088802c7f2b4cc08fd308301d309e71 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-21T18:56:42Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-0088802c7f2b4cc08fd308301d309e712022-12-21T18:53:36ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362020-12-0120100949Acute idiopathic blind spot enlargement syndrome following influenza vaccinationXavier Quinones, MD0Jan Ortiz, MD1Carmen Santos, MD2Armando L. Oliver, MD3Julio Rodríguez, MD4Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USADepartment of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USADepartment of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USACorresponding author. UPR Department of Ophthalmology, PO BOX 3650689, San Juan, PR, 00936, USA.; Department of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USADepartment of Ophthalmology, University of Puerto Rico School of Medicine, Medical Sciences Campus, San Juan, PR, 00921, USAPurpose: To report a case of acute idiopathic blind spot enlargement syndrome (AIBSES) following influenza vaccination. Observations: A 57-year old woman presented with a one-month history of photopsia, temporal visual field disturbance on the right eye, 11 days following the administration of the influenza virus vaccine. Visual acuity was 20/30, and color vision remained normal. Examination revealed mild venular dilation at the edge of the right optic disk and was otherwise unremarkable. Visual field testing revealed enlargement of the right physiological blind spot. Medical workup, including brain CT scan, brain MRI, RPR, Treponema pallidum antibodies, Chest X-Ray, ANA, and PPD testing, was found within normal limits. Ancillary testing was compatible with an assessment of AIBSES secondary to influenza virus vaccination. Conclusions and Importance: Although direct causation may not be absolutely established by a single report, our case suggests that the influenza virus vaccine may serve as an immunological trigger for some cases of AIBSES. Thoughtful vaccination history is of the utmost importance when evaluating patients with AIBSES, as it may help elucidate the underlying precipitating factor. To our knowledge, this is the first reported case of AIBSES following influenza virus vaccination.http://www.sciencedirect.com/science/article/pii/S2451993620302644Acute blind spot enlargement syndromeInfluenza virusVaccination |
| spellingShingle | Xavier Quinones, MD Jan Ortiz, MD Carmen Santos, MD Armando L. Oliver, MD Julio Rodríguez, MD Acute idiopathic blind spot enlargement syndrome following influenza vaccination American Journal of Ophthalmology Case Reports Acute blind spot enlargement syndrome Influenza virus Vaccination |
| title | Acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| title_full | Acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| title_fullStr | Acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| title_full_unstemmed | Acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| title_short | Acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| title_sort | acute idiopathic blind spot enlargement syndrome following influenza vaccination |
| topic | Acute blind spot enlargement syndrome Influenza virus Vaccination |
| url | http://www.sciencedirect.com/science/article/pii/S2451993620302644 |
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