Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety.

Synthesis, characterization and in vitro antitrypanosomal activities of new carboxamides bearing quinoline moiety.

The reported toxicities of current antitrypanosomal drugs and the emergence of drug resistant trypanosomes underscore the need for the development of new antitrypanosomal agents. We report herein the synthesis and antitrypanosomal activity of 24 new amide derivatives of 3-aminoquinoline, bearing sub...

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Bibliographic Details
Main Authors: David Izuchukwu Ugwu, Uchechukwu Chris Okoro, Narendra Kumar Mishra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5764481?pdf=render

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