Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison
Abstract Background To compare the visual outcome and patients’ satisfaction after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) performed on fellow eyes of the same patients. Methods In this retrospective study, the...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | Eye and Vision |
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| Online Access: | http://link.springer.com/article/10.1186/s40662-020-00191-6 |
| _version_ | 1818341769912254464 |
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| author | Rita Mencucci Eleonora Favuzza Elisa Marziali Michela Cennamo Cosimo Mazzotta Ersilia Lucenteforte Gianni Virgili Stanislao Rizzo |
| author_facet | Rita Mencucci Eleonora Favuzza Elisa Marziali Michela Cennamo Cosimo Mazzotta Ersilia Lucenteforte Gianni Virgili Stanislao Rizzo |
| author_sort | Rita Mencucci |
| collection | DOAJ |
| description | Abstract Background To compare the visual outcome and patients’ satisfaction after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) performed on fellow eyes of the same patients. Methods In this retrospective study, the records of 18 pseudophakic patients affected by Fuchs endothelial dystrophy who underwent DMEK in one eye and UT-DSAEK in the fellow eye were reviewed. Best corrected visual acuity (BCVA), corneal pachymetry, keratometry, corneal aberrations, photopic and mesopic contrast sensitivity, and endothelial cell counts measured 12 months after surgery in either eye were analyzed and compared. The results of a satisfaction questionnaire were also reviewed. Results Twelve months after surgery, BCVA was not significantly different in UT-DSAEK and DMEK eyes (0.10 ± 0.04 and 0.07 ± 0.07 logMAR, respectively); at both 4- and 6 mm optical zones total and posterior corneal higher order aberrations (HOAs), posterior astigmatism and total coma were significantly lower after DMEK; BCVA in both groups was significantly correlated mainly with anterior corneal aberrations; contrast sensitivity was higher after DMEK especially in mesopic conditions and at medium spatial frequencies; the endothelial cell density was similar, although slightly higher in the UT-DSAEK group (p = 0.10). The satisfaction questionnaire showed that although patients were highly satisfied from both procedures, more than half of them preferred DMEK and reported a more comfortable and quicker postoperative recovery. Conclusions DMEK and UT-DSAEK showed no evidence of difference in terms of postoperative BCVA, although DMEK had a better performance in terms of contrast sensitivity, posterior corneal aberrations and overall patient satisfaction. |
| first_indexed | 2024-12-13T16:04:04Z |
| format | Article |
| id | doaj.art-008c906ee45f48d1b51bfffe20b35421 |
| institution | Directory Open Access Journal |
| issn | 2326-0254 |
| language | English |
| last_indexed | 2024-12-13T16:04:04Z |
| publishDate | 2020-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Eye and Vision |
| spelling | doaj.art-008c906ee45f48d1b51bfffe20b354212022-12-21T23:39:05ZengBMCEye and Vision2326-02542020-05-01711910.1186/s40662-020-00191-6Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparisonRita Mencucci0Eleonora Favuzza1Elisa Marziali2Michela Cennamo3Cosimo Mazzotta4Ersilia Lucenteforte5Gianni Virgili6Stanislao Rizzo7Eye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceEye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceEye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceEye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceDepartment of Medicine, Surgery and Neurosciences, Ophthalmology Unit, Siena UniversityDepartment of Clinical and Experimental medicine, University of PisaEye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceEye Clinic, Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA), University of FlorenceAbstract Background To compare the visual outcome and patients’ satisfaction after ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK) performed on fellow eyes of the same patients. Methods In this retrospective study, the records of 18 pseudophakic patients affected by Fuchs endothelial dystrophy who underwent DMEK in one eye and UT-DSAEK in the fellow eye were reviewed. Best corrected visual acuity (BCVA), corneal pachymetry, keratometry, corneal aberrations, photopic and mesopic contrast sensitivity, and endothelial cell counts measured 12 months after surgery in either eye were analyzed and compared. The results of a satisfaction questionnaire were also reviewed. Results Twelve months after surgery, BCVA was not significantly different in UT-DSAEK and DMEK eyes (0.10 ± 0.04 and 0.07 ± 0.07 logMAR, respectively); at both 4- and 6 mm optical zones total and posterior corneal higher order aberrations (HOAs), posterior astigmatism and total coma were significantly lower after DMEK; BCVA in both groups was significantly correlated mainly with anterior corneal aberrations; contrast sensitivity was higher after DMEK especially in mesopic conditions and at medium spatial frequencies; the endothelial cell density was similar, although slightly higher in the UT-DSAEK group (p = 0.10). The satisfaction questionnaire showed that although patients were highly satisfied from both procedures, more than half of them preferred DMEK and reported a more comfortable and quicker postoperative recovery. Conclusions DMEK and UT-DSAEK showed no evidence of difference in terms of postoperative BCVA, although DMEK had a better performance in terms of contrast sensitivity, posterior corneal aberrations and overall patient satisfaction.http://link.springer.com/article/10.1186/s40662-020-00191-6DMEKUT-DSAEKDSAEKDescemet stripping automated endothelial keratoplastyUltra-thin Descemet stripping automated endothelial keratoplastyDescemet membrane endothelial keratoplasty |
| spellingShingle | Rita Mencucci Eleonora Favuzza Elisa Marziali Michela Cennamo Cosimo Mazzotta Ersilia Lucenteforte Gianni Virgili Stanislao Rizzo Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison Eye and Vision DMEK UT-DSAEK DSAEK Descemet stripping automated endothelial keratoplasty Ultra-thin Descemet stripping automated endothelial keratoplasty Descemet membrane endothelial keratoplasty |
| title | Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison |
| title_full | Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison |
| title_fullStr | Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison |
| title_full_unstemmed | Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison |
| title_short | Ultrathin Descemet stripping automated endothelial keratoplasty versus Descemet membrane endothelial keratoplasty: a fellow-eye comparison |
| title_sort | ultrathin descemet stripping automated endothelial keratoplasty versus descemet membrane endothelial keratoplasty a fellow eye comparison |
| topic | DMEK UT-DSAEK DSAEK Descemet stripping automated endothelial keratoplasty Ultra-thin Descemet stripping automated endothelial keratoplasty Descemet membrane endothelial keratoplasty |
| url | http://link.springer.com/article/10.1186/s40662-020-00191-6 |
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