Intrapulmonary shunting is a key contributor to hypoxia in COVID-19: An update on the pathophysiology

<h4>Background</h4> The pathophysiology of COVID-19 remains poorly understood. We aimed to estimate the contribution of intrapulmonary shunting and ventilation-to-perfusion (VA/Q) mismatch using a mathematical model to construct oxygen-haemoglobin dissociation curves (ODCs). <h4>Me...

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Bibliographic Details
Main Authors: Nikhil Mayor, Harry Knights, Aleksandra Kotwica, Andrew Solomon Joseph Coppola, Harriet Hunter, Nathan Jeffreys, Alexander Morgan, Shivani Gupta, James Prentice, Rebecca Macfarlane, Emma Russell-Jones, Theodore Dassios, David Russell-Jones
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584408/?tool=EBI