LAMA3 DNA methylation and transcriptome changes associated with chemotherapy resistance in ovarian cancer

LAMA3 DNA methylation and transcriptome changes associated with chemotherapy resistance in ovarian cancer

Abstract Objective LAMA3 is a widely studied methylated gene in multiple tumors, but the relationship between chemotherapy resistance in ovarian cancer is unclear. In this study, LAMA3 methylation was predicted by bioinformatics, and the ability of LAMA3 methylation to predict the chemotherapy resis...

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Bibliographic Details
Main Authors: Li-yuan Feng, Yong-zhi Huang, Wei Zhang, Li Li
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Ovarian Research
Subjects:
Ovarian cancer
Chemoresistance
LAMA3 methylation
Prognosis
Online Access:https://doi.org/10.1186/s13048-021-00807-y

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