New Thienobenzo/Naphtho-Triazoles as Butyrylcholinesterase Inhibitors: Design, Synthesis and Computational Study

New Thienobenzo/Naphtho-Triazoles as Butyrylcholinesterase Inhibitors: Design, Synthesis and Computational Study

This study aims to test the inhibition potency of new thienobenzo/naphtho-triazoles toward cholinesterases, evaluate their inhibition selectivity, and interpret the obtained results by molecular modeling. The synthesis of 19 new thienobenzo/naphtho-triazoles by two different approaches resulted in a...

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Bibliographic Details
Main Authors: Milena Mlakić, Ida Selec, Irena Ćaleta, Ilijana Odak, Danijela Barić, Ana Ratković, Krešimir Molčanov, Irena Škorić
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
cholinesterases
photochemistry
synthesis
1,2,3-triazoles
inhibition
Online Access:https://www.mdpi.com/1422-0067/24/6/5879

Internet

https://www.mdpi.com/1422-0067/24/6/5879

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