A comparison of the test-negative and the matched case-control study designs for estimation of EV71 vaccine immunological surrogate endpoints from a randomized controlled trial

A comparison of the test-negative and the matched case-control study designs for estimation of EV71 vaccine immunological surrogate endpoints from a randomized controlled trial

Since TND could be an appropriate method to assess vaccine effectiveness, we want to know whether it may be used for the estimation of vaccine immunological surrogate endpoints, like case-control study. We conducted two study designs (test-negative design (TND) VS matched case-control design (MCC))...

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Bibliographic Details
Main Authors: Li Zhang, Pengfei Jin, Mingwei Wei, Hudachuan Jiang, Jingxin Li, Fengcai Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
test-negative design
ev71 vaccine
immunological surrogate endpoints
Online Access:http://dx.doi.org/10.1080/21645515.2022.2073751

Internet

http://dx.doi.org/10.1080/21645515.2022.2073751

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