Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies
Pathochemical characteristic features of facial nerve neuropathy (FNN) have been more accurately defined. Heterogeneous patochemical pattern of facial nerve neuropathy has been shown to be dependent on the severity of the disease, intensity of free radical oxidation processes, and hormonal status of...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/285 |
| _version_ | 1797759090678562816 |
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| author | L. V. Govorova N. V. Skripchenko D. A. Golyakov N. F. Pulman |
| author_facet | L. V. Govorova N. V. Skripchenko D. A. Golyakov N. F. Pulman |
| author_sort | L. V. Govorova |
| collection | DOAJ |
| description | Pathochemical characteristic features of facial nerve neuropathy (FNN) have been more accurately defined. Heterogeneous patochemical pattern of facial nerve neuropathy has been shown to be dependent on the severity of the disease, intensity of free radical oxidation processes, and hormonal status of the patient. We have found reliable distinctions in dynamics of free radical oxidation processes, and hormo-nal status in the blood of the patients with moderately severe and severe forms of facial nerve neuropathies. In facial nerve neuropathies we observed regulatory effects of cortisol and somatotropic hormone; in facial nerve neuropathywith moderate severity the hormones of thyroid group were seen to be switching off, falling out the processes regulating metabolism. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) were found to have regulating effects, especially in the acute phase of the disease. Different dynamics of the hormones in patients with high and low free radical oxidation levels suggests that the oxidative stress intensity could be associated with regulatory effects of the hormones . The results of correlation analysis confirm the reliable distinctions in free radical oxidation characteristics andand cortisole levels, STH, FSH and LH levels. |
| first_indexed | 2024-03-12T18:39:27Z |
| format | Article |
| id | doaj.art-009a5a9b47d64836b035865f51442622 |
| institution | Directory Open Access Journal |
| issn | 2072-6732 |
| language | Russian |
| last_indexed | 2024-03-12T18:39:27Z |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj.art-009a5a9b47d64836b035865f514426222023-08-02T07:52:22ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0121515810.22625/2072-6732-2010-2-1-51-58299Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathiesL. V. Govorova0N. V. Skripchenko1D. A. Golyakov2N. F. Pulman3Научно-исследовательский институт детских инфекций ФМБА России, г. Санкт-ПетербургНаучно-исследовательский институт детских инфекций ФМБА России, г. Санкт-ПетербургАрхангельская областная клиническая больница, АрхангельскНаучно-исследовательский институт детских инфекций ФМБА России, г. Санкт-ПетербургPathochemical characteristic features of facial nerve neuropathy (FNN) have been more accurately defined. Heterogeneous patochemical pattern of facial nerve neuropathy has been shown to be dependent on the severity of the disease, intensity of free radical oxidation processes, and hormonal status of the patient. We have found reliable distinctions in dynamics of free radical oxidation processes, and hormo-nal status in the blood of the patients with moderately severe and severe forms of facial nerve neuropathies. In facial nerve neuropathies we observed regulatory effects of cortisol and somatotropic hormone; in facial nerve neuropathywith moderate severity the hormones of thyroid group were seen to be switching off, falling out the processes regulating metabolism. Follicle stimulating hormone (FSH) and luteinizing hormone (LH) were found to have regulating effects, especially in the acute phase of the disease. Different dynamics of the hormones in patients with high and low free radical oxidation levels suggests that the oxidative stress intensity could be associated with regulatory effects of the hormones . The results of correlation analysis confirm the reliable distinctions in free radical oxidation characteristics andand cortisole levels, STH, FSH and LH levels.https://journal.niidi.ru/jofin/article/view/285невропатия лицевого нервадетисвободно-радикальное окислениегормоны: соматотропный гормонкортизолфолликулостимулирующий и лютеинизирующий гормоны |
| spellingShingle | L. V. Govorova N. V. Skripchenko D. A. Golyakov N. F. Pulman Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies Журнал инфектологии невропатия лицевого нерва дети свободно-радикальное окисление гормоны: соматотропный гормон кортизол фолликулостимулирующий и лютеинизирующий гормоны |
| title | Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| title_full | Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| title_fullStr | Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| title_full_unstemmed | Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| title_short | Hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| title_sort | hormonal shifts and intensity of free radical oxidation in the blood of patients with facial nerve neuropathies |
| topic | невропатия лицевого нерва дети свободно-радикальное окисление гормоны: соматотропный гормон кортизол фолликулостимулирующий и лютеинизирующий гормоны |
| url | https://journal.niidi.ru/jofin/article/view/285 |
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