Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil
CONTEXT: Human DNA identification is a powerful tool for paternity cases as well as for criminal investigation, in which biological evidence is typed after collection from crime scenes and for the identification of human remains. OBJECTIVE: Identification of a criminal in a rape case with 4 suspects...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Associação Paulista de Medicina
2002-05-01
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| Series: | São Paulo Medical Journal |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802002000300004&lng=en&tlng=en |
| _version_ | 1819089865202991104 |
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| author | Andréa Carla de Souza Góes Dayse Aparecida da Silva Cristiane Santana Domingues João Marreiro Sobrinho Elizeu Fagundes de Carvalho |
| author_facet | Andréa Carla de Souza Góes Dayse Aparecida da Silva Cristiane Santana Domingues João Marreiro Sobrinho Elizeu Fagundes de Carvalho |
| author_sort | Andréa Carla de Souza Góes |
| collection | DOAJ |
| description | CONTEXT: Human DNA identification is a powerful tool for paternity cases as well as for criminal investigation, in which biological evidence is typed after collection from crime scenes and for the identification of human remains. OBJECTIVE: Identification of a criminal in a rape case with 4 suspects using STR and VNTR DNA analysis. TYPE OF STUDY: Forensic DNA analysis. SETTING: DNA Diagnostic Laboratory, Universidade Estadual do Rio de Janeiro, Brazil. PARTICIPANTS: Blood from 4 suspects and the victim, and skin from the fetus. PROCEDURES: Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). RESULTS: Three of the suspects were excluded and one of them was identified as the biological father of the fetus after typing with CTT and FFv Multiplexes. Complementary DNA typing at 3 VNTR loci was also carried out. CONCLUSIONS: After typing four suspects using 6 STR loci, one of them was identified as the biological father of the fetus. In order to significantly enhance the Combined Paternity Index (PI), complementary DNA typing in 3 VNTR loci was carried out. The included suspect was found to be the biological father with a PI of 412,860 (Probability of Paternity: 99.9997%). |
| first_indexed | 2024-12-21T22:14:43Z |
| format | Article |
| id | doaj.art-009cc9ddd0674902a661256831485a65 |
| institution | Directory Open Access Journal |
| issn | 1806-9460 |
| language | English |
| last_indexed | 2024-12-21T22:14:43Z |
| publishDate | 2002-05-01 |
| publisher | Associação Paulista de Medicina |
| record_format | Article |
| series | São Paulo Medical Journal |
| spelling | doaj.art-009cc9ddd0674902a661256831485a652022-12-21T18:48:29ZengAssociação Paulista de MedicinaSão Paulo Medical Journal1806-94602002-05-011203777910.1590/S1516-31802002000300004S1516-31802002000300004Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, BrazilAndréa Carla de Souza Góes0Dayse Aparecida da Silva1Cristiane Santana Domingues2João Marreiro Sobrinho3Elizeu Fagundes de Carvalho4Universidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroCONTEXT: Human DNA identification is a powerful tool for paternity cases as well as for criminal investigation, in which biological evidence is typed after collection from crime scenes and for the identification of human remains. OBJECTIVE: Identification of a criminal in a rape case with 4 suspects using STR and VNTR DNA analysis. TYPE OF STUDY: Forensic DNA analysis. SETTING: DNA Diagnostic Laboratory, Universidade Estadual do Rio de Janeiro, Brazil. PARTICIPANTS: Blood from 4 suspects and the victim, and skin from the fetus. PROCEDURES: Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP). RESULTS: Three of the suspects were excluded and one of them was identified as the biological father of the fetus after typing with CTT and FFv Multiplexes. Complementary DNA typing at 3 VNTR loci was also carried out. CONCLUSIONS: After typing four suspects using 6 STR loci, one of them was identified as the biological father of the fetus. In order to significantly enhance the Combined Paternity Index (PI), complementary DNA typing in 3 VNTR loci was carried out. The included suspect was found to be the biological father with a PI of 412,860 (Probability of Paternity: 99.9997%).http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802002000300004&lng=en&tlng=enSexual abuseForensic DNASTRVNTRPaternity |
| spellingShingle | Andréa Carla de Souza Góes Dayse Aparecida da Silva Cristiane Santana Domingues João Marreiro Sobrinho Elizeu Fagundes de Carvalho Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil São Paulo Medical Journal Sexual abuse Forensic DNA STR VNTR Paternity |
| title | Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil |
| title_full | Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil |
| title_fullStr | Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil |
| title_full_unstemmed | Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil |
| title_short | Identification of a criminal by DNA typing in a rape case in Rio de Janeiro, Brazil |
| title_sort | identification of a criminal by dna typing in a rape case in rio de janeiro brazil |
| topic | Sexual abuse Forensic DNA STR VNTR Paternity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802002000300004&lng=en&tlng=en |
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