Single-cell RNA sequencing to detect age-associated genes that identify senescent cells in the liver of aged mice

Abstract Senescent cells are predicted to occur and increase in animal tissues with aging. However, senescent cells in the tissues of aged animals remain to be identified. We refer to the marker genes to identify senescent cells in tissues as “age-associated genes”. In this study, we searched for ag...

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Bibliographic Details
Main Authors: Yuta Doshida, Shinichi Hashimoto, Sadahiro Iwabuchi, Yuka Takino, Toshiyuki Ishiwata, Toshiro Aigaki, Akihito Ishigami
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41352-6