Surface Engineering Methods for Powder Bed Printed Tablets to Optimize External Smoothness and Facilitate the Application of Different Coatings

Surface Engineering Methods for Powder Bed Printed Tablets to Optimize External Smoothness and Facilitate the Application of Different Coatings

In a previous attempt to achieve ileo-colonic targeting of bovine intestinal alkaline phosphatase (BIAP), we applied a pH-dependent coating, the ColoPulse coating, directly on powder bed printed (PBP) tablets. However, the high surface roughness necessitated an additional sub-coating layer [Nguyen,...

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Bibliographic Details
Main Authors: Khanh T. T. Nguyen, Daan Zillen, Franca F. M. van Heijningen, Kjeld J. C. van Bommel, Renz J. van Ee, Henderik W. Frijlink, Wouter L. J. Hinrichs
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
3D printing
powder bed printing
personalized medicine
biologics
formulation
surface analysis
Online Access:https://www.mdpi.com/1999-4923/15/9/2193

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