Magnetic Resonance Imaging Correlates of White Matter Gliosis and Injury in Preterm Fetal Sheep Exposed to Progressive Systemic Inflammation

Magnetic Resonance Imaging Correlates of White Matter Gliosis and Injury in Preterm Fetal Sheep Exposed to Progressive Systemic Inflammation

Progressive fetal infection/inflammation is strongly associated with neural injury after preterm birth. We aimed to test the hypotheses that progressively developing fetal inflammation leads to neuroinflammation and impaired white matter development and that the histopathological changes can be dete...

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Bibliographic Details
Main Authors: Robert Galinsky, Yohan van de Looij, Natasha Mitchell, Justin M. Dean, Simerdeep K. Dhillon, Kyohei Yamaguchi, Christopher A. Lear, Guido Wassink, Joanne O. Davidson, Fraser Nott, Valerie A. Zahra, Sharmony B. Kelly, Victoria J. King, Stéphane V. Sizonenko, Laura Bennet, Alistair J. Gunn
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
preterm infant
inflammation
infection
brain
MRI
Online Access:https://www.mdpi.com/1422-0067/21/23/8891

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