Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications
Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their uniqu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2012-11-01
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| Series: | Micromachines |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2072-666X/3/4/615 |
| _version_ | 1811272059920056320 |
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| author | Ken-Tye Yong Indrajit Roy Rui Hu Peiyi Song Danny Jian Hang Tng |
| author_facet | Ken-Tye Yong Indrajit Roy Rui Hu Peiyi Song Danny Jian Hang Tng |
| author_sort | Ken-Tye Yong |
| collection | DOAJ |
| description | Despite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges. |
| first_indexed | 2024-04-12T22:33:27Z |
| format | Article |
| id | doaj.art-00a80af4216b4c569e7443fe5c348e00 |
| institution | Directory Open Access Journal |
| issn | 2072-666X |
| language | English |
| last_indexed | 2024-04-12T22:33:27Z |
| publishDate | 2012-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Micromachines |
| spelling | doaj.art-00a80af4216b4c569e7443fe5c348e002022-12-22T03:13:55ZengMDPI AGMicromachines2072-666X2012-11-013461563110.3390/mi3040615Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo ApplicationsKen-Tye YongIndrajit RoyRui HuPeiyi SongDanny Jian Hang TngDespite the advancements made in drug delivery systems over the years, many challenges remain in drug delivery systems for treating chronic diseases at the personalized medicine level. The current urgent need is to develop novel strategies for targeted therapy of chronic diseases. Due to their unique properties, microelectromechanical systems (MEMS) technology has been recently engineered as implantable drug delivery systems for disease therapy. This review examines the challenges faced in implementing implantable MEMS drug delivery systems in vivo and the solutions available to overcome these challenges.http://www.mdpi.com/2072-666X/3/4/615MEMS devicedrug deliverybiomedical applicationsimplantable |
| spellingShingle | Ken-Tye Yong Indrajit Roy Rui Hu Peiyi Song Danny Jian Hang Tng Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications Micromachines MEMS device drug delivery biomedical applications implantable |
| title | Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications |
| title_full | Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications |
| title_fullStr | Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications |
| title_full_unstemmed | Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications |
| title_short | Approaches and Challenges of Engineering Implantable Microelectromechanical Systems (MEMS) Drug Delivery Systems for in Vitro and in Vivo Applications |
| title_sort | approaches and challenges of engineering implantable microelectromechanical systems mems drug delivery systems for in vitro and in vivo applications |
| topic | MEMS device drug delivery biomedical applications implantable |
| url | http://www.mdpi.com/2072-666X/3/4/615 |
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