Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens
Practice of layer poultry farming and commercial egg production relies on the optimal use and improvement of the welfare and genetically determined functional abilities of laying hens, their efficient intake of feed and its components, adaptation to housing conditions and resistance to infectious di...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-12-01
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| Series: | Italian Journal of Animal Science |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/1828051X.2020.1733445 |
| _version_ | 1818443745491681280 |
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| author | Valeriy G. Narushin Georgi Yu. Laptev Elena A. Yildirim Larisa A. Ilina Valentina A. Filippova Ivan I. Kochish Elena P. Gorfunkel Andrei V. Dubrovin Natalia I. Novikova Oksana B. Novikova Timur P. Dunyashev Vladimir I. Smolensky Peter F. Surai Yuri V. Bondarenko Darren K. Griffin Michael N. Romanov |
| author_facet | Valeriy G. Narushin Georgi Yu. Laptev Elena A. Yildirim Larisa A. Ilina Valentina A. Filippova Ivan I. Kochish Elena P. Gorfunkel Andrei V. Dubrovin Natalia I. Novikova Oksana B. Novikova Timur P. Dunyashev Vladimir I. Smolensky Peter F. Surai Yuri V. Bondarenko Darren K. Griffin Michael N. Romanov |
| author_sort | Valeriy G. Narushin |
| collection | DOAJ |
| description | Practice of layer poultry farming and commercial egg production relies on the optimal use and improvement of the welfare and genetically determined functional abilities of laying hens, their efficient intake of feed and its components, adaptation to housing conditions and resistance to infectious diseases including salmonellosis. Previous studies were focussed on relationships of chicken performance and resistance with the expression profiles of individual genes involved in metabolic processes and immune system, or with genetic markers that can be closely associated with these processes in chickens. In this study, mathematical models of coherent changes in laying hens were developed for the expression of eight genes involved in immunity and metabolism, on the one hand, and biochemical and immunological blood parameters, on the other hand, in response to Salmonella infection and administration of a phytobiotic Intebio. The proposed modelling approach can be a further basis for an in-depth research of the relationship between the gene expression, functional state and welfare of poultry, impact of pathogenic microorganisms and use of immunomodulatory drugs.HIGHLIGHTS Improved egg production and resistance rely on hens’ potential in gene expression and metabolism. We developed mathematical models for coherent responses of hens’ gene expression and blood indices to Salmonella infection and phytobiotic intake. This approach can be used for further studying relationship between gene expression, functional state, impact of pathogens and antimicrobial drugs. |
| first_indexed | 2024-12-14T19:04:55Z |
| format | Article |
| id | doaj.art-00aee08563824c898aabd06b9663ed8d |
| institution | Directory Open Access Journal |
| issn | 1594-4077 1828-051X |
| language | English |
| last_indexed | 2024-12-14T19:04:55Z |
| publishDate | 2020-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj.art-00aee08563824c898aabd06b9663ed8d2022-12-21T22:50:53ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2020-12-0119128228710.1080/1828051X.2020.17334451733445Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hensValeriy G. Narushin0Georgi Yu. Laptev1Elena A. Yildirim2Larisa A. Ilina3Valentina A. Filippova4Ivan I. Kochish5Elena P. Gorfunkel6Andrei V. Dubrovin7Natalia I. Novikova8Oksana B. Novikova9Timur P. Dunyashev10Vladimir I. Smolensky11Peter F. Surai12Yuri V. Bondarenko13Darren K. Griffin14Michael N. Romanov15Vita-Market LtdBIOTROF + Ltd, PushkinBIOTROF + Ltd, PushkinBIOTROF + Ltd, PushkinBIOTROF + Ltd, PushkinK. I. Skryabin Moscow State Academy of Veterinary Medicine and BiotechnologyBIOTROF + Ltd, PushkinBIOTROF + Ltd, PushkinBIOTROF + Ltd, PushkinAll-Russian Veterinary Research Institute of Poultry Science – Branch of the Federal State Budget Scientific Institution Federal Scientific Centre ‘All-Russian Poultry Research and Technological Institute’ of the Russian Academy of SciencesBIOTROF + Ltd, PushkinK. I. Skryabin Moscow State Academy of Veterinary Medicine and BiotechnologyK. I. Skryabin Moscow State Academy of Veterinary Medicine and BiotechnologyDepartment of Feed and Animal Feeding Technologies, Faculty of Biology and Technology, Sumy National Agrarian UniversitySchool of Biosciences, University of KentK. I. Skryabin Moscow State Academy of Veterinary Medicine and BiotechnologyPractice of layer poultry farming and commercial egg production relies on the optimal use and improvement of the welfare and genetically determined functional abilities of laying hens, their efficient intake of feed and its components, adaptation to housing conditions and resistance to infectious diseases including salmonellosis. Previous studies were focussed on relationships of chicken performance and resistance with the expression profiles of individual genes involved in metabolic processes and immune system, or with genetic markers that can be closely associated with these processes in chickens. In this study, mathematical models of coherent changes in laying hens were developed for the expression of eight genes involved in immunity and metabolism, on the one hand, and biochemical and immunological blood parameters, on the other hand, in response to Salmonella infection and administration of a phytobiotic Intebio. The proposed modelling approach can be a further basis for an in-depth research of the relationship between the gene expression, functional state and welfare of poultry, impact of pathogenic microorganisms and use of immunomodulatory drugs.HIGHLIGHTS Improved egg production and resistance rely on hens’ potential in gene expression and metabolism. We developed mathematical models for coherent responses of hens’ gene expression and blood indices to Salmonella infection and phytobiotic intake. This approach can be used for further studying relationship between gene expression, functional state, impact of pathogens and antimicrobial drugs.http://dx.doi.org/10.1080/1828051X.2020.1733445coherent changeslaying hensmodellingsalmonellaphytobiotic |
| spellingShingle | Valeriy G. Narushin Georgi Yu. Laptev Elena A. Yildirim Larisa A. Ilina Valentina A. Filippova Ivan I. Kochish Elena P. Gorfunkel Andrei V. Dubrovin Natalia I. Novikova Oksana B. Novikova Timur P. Dunyashev Vladimir I. Smolensky Peter F. Surai Yuri V. Bondarenko Darren K. Griffin Michael N. Romanov Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens Italian Journal of Animal Science coherent changes laying hens modelling salmonella phytobiotic |
| title | Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens |
| title_full | Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens |
| title_fullStr | Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens |
| title_full_unstemmed | Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens |
| title_short | Modelling effects of phytobiotic administration on coherent responses to Salmonella infection in laying hens |
| title_sort | modelling effects of phytobiotic administration on coherent responses to salmonella infection in laying hens |
| topic | coherent changes laying hens modelling salmonella phytobiotic |
| url | http://dx.doi.org/10.1080/1828051X.2020.1733445 |
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