Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy
<i>Background:</i> Since the advent of a new generation of inflow-sensitive inversion recovery (IFIR) technology, three-dimensional non-contrast-enhanced magnetic resonance angiography is being used to obtain hepatic vessel images without applying gadolinium contrast agent. The purpose o...
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MDPI AG
2022-02-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/2/498 |
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| author | Chien-Chang Liao Meng-Hsiang Chen Chun-Yen Yu Leung-Chit Leo Tsang Chao-Long Chen Hsien-Wen Hsu Wei-Xiong Lim Yi-Hsuan Chuang Po-Hsun Huang Yu-Fan Cheng Hsin-You Ou |
| author_facet | Chien-Chang Liao Meng-Hsiang Chen Chun-Yen Yu Leung-Chit Leo Tsang Chao-Long Chen Hsien-Wen Hsu Wei-Xiong Lim Yi-Hsuan Chuang Po-Hsun Huang Yu-Fan Cheng Hsin-You Ou |
| author_sort | Chien-Chang Liao |
| collection | DOAJ |
| description | <i>Background:</i> Since the advent of a new generation of inflow-sensitive inversion recovery (IFIR) technology, three-dimensional non-contrast-enhanced magnetic resonance angiography is being used to obtain hepatic vessel images without applying gadolinium contrast agent. The purpose of this study was to explore the diagnostic efficacy of non-contrast-enhanced magnetic resonance angiography (non-CE MRA), contrast-enhanced magnetic resonance angiography (CMRA), and computed tomography angiography (CTA) in the preoperative evaluation of living liver donors. <i>Methods:</i> A total of 43 liver donor candidates who were evaluated for living donor liver transplantation completed examinations. Donors’ age, gender, renal function (eGFR), and previous CTA and imaging were recorded before non-CE MRA and CMRA. CTA images were used as the standard. <i>Results:</i> Five different classifications of hepatic artery patterns (types I, III, V, VI, VIII) and three different classifications of portal vein patterns (types I, II, and III) were identified among 43 candidates. The pretransplant vascular anatomy was well identified using combined non-CE MRA and CMRA of hepatic arteries (100%), PVs (98%), and hepatic veins (100%) compared with CTA images. Non-CE MRA images had significantly stronger contrast signal intensity of portal veins (<i>p</i> < 0.01) and hepatic veins (<i>p</i> < 0.01) than CMRA. No differences were found in signal intensity of the hepatic artery between non-CE MRA and CMRA. <i>Conclusion:</i> Combined non-CE MRA and CMRA demonstrate comparable diagnostic ability to CTA and provide enhanced biliary anatomy information that assures optimum donor safety. |
| first_indexed | 2024-03-09T22:09:59Z |
| format | Article |
| id | doaj.art-00af84fc44a548b3a230d4d7c0b6e3da |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T22:09:59Z |
| publishDate | 2022-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-00af84fc44a548b3a230d4d7c0b6e3da2023-11-23T19:33:08ZengMDPI AGDiagnostics2075-44182022-02-0112249810.3390/diagnostics12020498Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular AnatomyChien-Chang Liao0Meng-Hsiang Chen1Chun-Yen Yu2Leung-Chit Leo Tsang3Chao-Long Chen4Hsien-Wen Hsu5Wei-Xiong Lim6Yi-Hsuan Chuang7Po-Hsun Huang8Yu-Fan Cheng9Hsin-You Ou10Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, TaiwanDepartment of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, Taiwan<i>Background:</i> Since the advent of a new generation of inflow-sensitive inversion recovery (IFIR) technology, three-dimensional non-contrast-enhanced magnetic resonance angiography is being used to obtain hepatic vessel images without applying gadolinium contrast agent. The purpose of this study was to explore the diagnostic efficacy of non-contrast-enhanced magnetic resonance angiography (non-CE MRA), contrast-enhanced magnetic resonance angiography (CMRA), and computed tomography angiography (CTA) in the preoperative evaluation of living liver donors. <i>Methods:</i> A total of 43 liver donor candidates who were evaluated for living donor liver transplantation completed examinations. Donors’ age, gender, renal function (eGFR), and previous CTA and imaging were recorded before non-CE MRA and CMRA. CTA images were used as the standard. <i>Results:</i> Five different classifications of hepatic artery patterns (types I, III, V, VI, VIII) and three different classifications of portal vein patterns (types I, II, and III) were identified among 43 candidates. The pretransplant vascular anatomy was well identified using combined non-CE MRA and CMRA of hepatic arteries (100%), PVs (98%), and hepatic veins (100%) compared with CTA images. Non-CE MRA images had significantly stronger contrast signal intensity of portal veins (<i>p</i> < 0.01) and hepatic veins (<i>p</i> < 0.01) than CMRA. No differences were found in signal intensity of the hepatic artery between non-CE MRA and CMRA. <i>Conclusion:</i> Combined non-CE MRA and CMRA demonstrate comparable diagnostic ability to CTA and provide enhanced biliary anatomy information that assures optimum donor safety.https://www.mdpi.com/2075-4418/12/2/498contrast agenthepatic anatomyinflow-sensitive inversion recoveryliver transplantliving donorsignal intensity |
| spellingShingle | Chien-Chang Liao Meng-Hsiang Chen Chun-Yen Yu Leung-Chit Leo Tsang Chao-Long Chen Hsien-Wen Hsu Wei-Xiong Lim Yi-Hsuan Chuang Po-Hsun Huang Yu-Fan Cheng Hsin-You Ou Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy Diagnostics contrast agent hepatic anatomy inflow-sensitive inversion recovery liver transplant living donor signal intensity |
| title | Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy |
| title_full | Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy |
| title_fullStr | Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy |
| title_full_unstemmed | Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy |
| title_short | Non-Contrast-Enhanced and Contrast-Enhanced Magnetic Resonance Angiography in Living Donor Liver Vascular Anatomy |
| title_sort | non contrast enhanced and contrast enhanced magnetic resonance angiography in living donor liver vascular anatomy |
| topic | contrast agent hepatic anatomy inflow-sensitive inversion recovery liver transplant living donor signal intensity |
| url | https://www.mdpi.com/2075-4418/12/2/498 |
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