Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants
Electrochemical portable sensing systems can offer viable support in the analysis of environmental contaminants due to the compactness of their electronic components and overall simplicity of their detection principles. In the present work, a new electrochemical portable platform (EPP) with miniatur...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Engineering Proceedings |
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| Online Access: | https://www.mdpi.com/2673-4591/48/1/50 |
| _version_ | 1797241213224484864 |
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| author | Miguel Tavares Álvaro Torrinha Raquel Queirós João Piteira Cristina Delerue-Matos Simone Morais |
| author_facet | Miguel Tavares Álvaro Torrinha Raquel Queirós João Piteira Cristina Delerue-Matos Simone Morais |
| author_sort | Miguel Tavares |
| collection | DOAJ |
| description | Electrochemical portable sensing systems can offer viable support in the analysis of environmental contaminants due to the compactness of their electronic components and overall simplicity of their detection principles. In the present work, a new electrochemical portable platform (EPP) with miniaturized chip-integrated gold electrodes was developed and applied in the detection of the drug acetaminophen (APAP) as a model analyte. The produced miniaturized chip-integrated gold electrodes were first characterized via atomic force and scanning electron microscopy and integrated into the EPP, and subsequently the complete set-up was tested for electrochemical detection of APAP. The results showed adequate performance of the developed EPP when compared to a traditional electrochemical system under optimal conditions (pH 8, deposition potential 0.1 V, deposition time 240 s and scan rate of 50 mV.s<sup>−1</sup>), with a sensitivity of 1.6 μA.mM<sup>−1</sup> and limit of detection of 67 µM. The EPP was validated in river and wastewater samples, achieving recoveries ranging from 93.0 to 96.6%. |
| first_indexed | 2024-04-24T18:19:45Z |
| format | Article |
| id | doaj.art-00afa6e9fb8849b88b93e863907d508c |
| institution | Directory Open Access Journal |
| issn | 2673-4591 |
| language | English |
| last_indexed | 2024-04-24T18:19:45Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Engineering Proceedings |
| spelling | doaj.art-00afa6e9fb8849b88b93e863907d508c2024-03-27T13:36:10ZengMDPI AGEngineering Proceedings2673-45912023-10-014815010.3390/CSAC2023-14900Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical PollutantsMiguel Tavares0Álvaro Torrinha1Raquel Queirós2João Piteira3Cristina Delerue-Matos4Simone Morais5REQUIMTE/LAQV, ISEP, Polytechnic of Porto, rua Dr. António Bernardino de Almeida, 4249-015 Porto, PortugalREQUIMTE/LAQV, ISEP, Polytechnic of Porto, rua Dr. António Bernardino de Almeida, 4249-015 Porto, PortugalInternational Iberian Nanotechnology Laboratory, Avenida Mestre José Veiga, 4715-330 Braga, PortugalInternational Iberian Nanotechnology Laboratory, Avenida Mestre José Veiga, 4715-330 Braga, PortugalREQUIMTE/LAQV, ISEP, Polytechnic of Porto, rua Dr. António Bernardino de Almeida, 4249-015 Porto, PortugalREQUIMTE/LAQV, ISEP, Polytechnic of Porto, rua Dr. António Bernardino de Almeida, 4249-015 Porto, PortugalElectrochemical portable sensing systems can offer viable support in the analysis of environmental contaminants due to the compactness of their electronic components and overall simplicity of their detection principles. In the present work, a new electrochemical portable platform (EPP) with miniaturized chip-integrated gold electrodes was developed and applied in the detection of the drug acetaminophen (APAP) as a model analyte. The produced miniaturized chip-integrated gold electrodes were first characterized via atomic force and scanning electron microscopy and integrated into the EPP, and subsequently the complete set-up was tested for electrochemical detection of APAP. The results showed adequate performance of the developed EPP when compared to a traditional electrochemical system under optimal conditions (pH 8, deposition potential 0.1 V, deposition time 240 s and scan rate of 50 mV.s<sup>−1</sup>), with a sensitivity of 1.6 μA.mM<sup>−1</sup> and limit of detection of 67 µM. The EPP was validated in river and wastewater samples, achieving recoveries ranging from 93.0 to 96.6%.https://www.mdpi.com/2673-4591/48/1/50contaminants of emerging concernpharmaceuticalselectrochemical portable platformelectroanalysis |
| spellingShingle | Miguel Tavares Álvaro Torrinha Raquel Queirós João Piteira Cristina Delerue-Matos Simone Morais Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants Engineering Proceedings contaminants of emerging concern pharmaceuticals electrochemical portable platform electroanalysis |
| title | Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants |
| title_full | Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants |
| title_fullStr | Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants |
| title_full_unstemmed | Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants |
| title_short | Development of a Portable Electrochemical Platform with Chip-Integrated Gold Electrodes for Detection of Pharmaceutical Pollutants |
| title_sort | development of a portable electrochemical platform with chip integrated gold electrodes for detection of pharmaceutical pollutants |
| topic | contaminants of emerging concern pharmaceuticals electrochemical portable platform electroanalysis |
| url | https://www.mdpi.com/2673-4591/48/1/50 |
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