| Summary: | Aim: The aim of this study is to compare the results of conjunctival closure in pterygium surgery using fibrin adhesive versus vicryl sutures. Materials and Methods: This study was carried out in the premises of rural-based tertiary hospital. A comparative prospective study was performed in fifty patients (fifty eyes) with primary nasal pterygium. They were randomized to undergo pterygium surgery using either 8-0 vicryl sutures (25 eyes) or fibrin glue (25 eyes) to attach the conjunctival autograft from August 2014 to February 2015. Mean follow-up was 14 months. Outcome measures were duration of surgery, complication, postoperative discomfort, and recurrence of pterygium. Clinical assessment was performed on days at 1, 7, and 14 days, and every 2 months thereafter. Statistical Analysis: All data were evaluated by using SPSS version 19.0 (Released 2010, IBM SPSS Statistics for Windows, Version 19.0. Armonk, NY: IBM Corp.) package program. Mann-Whitney U-test was used for the comparison of symptoms and signs of two groups. Unpaired t-test was used to compare two groups in terms of surgery time as well as recurrence rates. Results: Average operative time was 15.76 min (range 12-20 min) in the fibrin glue and 33.56 min (range 30-45 min) in the suture group (P < 0.001). The symptoms such as pain, photophobia, foreign body sensation, watering and conjunctival, and chemosis were significantly less in the subjects treated with glue than suture (for chemosis and photophobia [P = 0.001]; for pain and watering [P < 0.001]). Three cases of recurrence in the suture group and one case of pyogenic granuloma in the fibrin glue group were reported. Conclusion: The use of fibrin glue in pterygium surgery significantly reduces operative time and patient symptoms, pain, and discomfort.
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