Structural effects of intra-articular TGF-β1 in moderate to advanced knee osteoarthritis: MRI-based assessment in a randomized controlled trial

Structural effects of intra-articular TGF-β1 in moderate to advanced knee osteoarthritis: MRI-based assessment in a randomized controlled trial

Abstract Background To determine effects of allogeneic human chondrocytes expressing TGF-β1 (TG-C) on structural progression of MRI features of knee osteoarthritis over a 1 year period. Methods This phase II randomized controlled trial of TG-C included patients with moderate to advanced osteoarthrit...

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Bibliographic Details
Main Authors: A. Guermazi, G. Kalsi, J. Niu, M. D. Crema, R. O. Copeland, A. Orlando, M. J. Noh, F. W. Roemer
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Musculoskeletal Disorders
Subjects:
Tgf-β1
Osteoarthritis
MRI
Randomized controlled trial
Online Access:http://link.springer.com/article/10.1186/s12891-017-1830-8

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