Functional Interactions of <i>Kluyveromyces lactis</i> Telomerase Reverse Transcriptase with the Three-Way Junction and the Template Domains of Telomerase RNA

Functional Interactions of <i>Kluyveromyces lactis</i> Telomerase Reverse Transcriptase with the Three-Way Junction and the Template Domains of Telomerase RNA

The ribonucleoprotein telomerase contains two essential components: telomerase RNA (TER) and telomerase reverse transcriptase (TERT, Est2 in yeast). A small portion of TER, termed the template, is copied by TERT onto the chromosome ends, thus compensating for sequence loss due to incomplete DNA repl...

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Bibliographic Details
Main Authors: Wasif Al-Shareef, Yogev Brown, Christopher Bryan, Elena Shuvaeva, Shhadeh Bsoul, Raanan Greenman, Majdi M. Kabaha, Nikolai B. Ulyanov, Emmanuel Skordalakes, Yehuda Tzfati
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
yeast
ribonucleoprotein
telomerase
telomerase RNA
three-way junction
Est2
Online Access:https://www.mdpi.com/1422-0067/23/18/10757

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