Significance of Siglec‐15 expression in colorectal cancer: association with advanced disease stage and fewer tumor‐infiltrating lymphocytes

Significance of Siglec‐15 expression in colorectal cancer: association with advanced disease stage and fewer tumor‐infiltrating lymphocytes

Abstract Siglec‐15, a novel immune suppressor, is upregulated in many human cancers. The aim of this study was to explore the expression of Siglec‐15 in colorectal cancer (CRC), and investigate whether Siglec‐15 could be a potential target for cancer immunotherapy in patients with CRC. We performed...

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Bibliographic Details
Main Authors: Zhao Lu, Pu Cheng, Fei Huang, Jiyun Li, Bingzhi Wang, Shuangmei Zou, Zhaoxu Zheng, Chunwei Peng
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:The Journal of Pathology: Clinical Research
Subjects:
Siglec‐15
PD‐L1
colorectal cancer
tumor‐infiltrating lymphocytes
Online Access:https://doi.org/10.1002/cjp2.303

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