Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin
Hypersensitivity pneumonitis is a potentially fatal immunological lung disease caused by occupational or environmental exposure to specific antigens and resulting from lymphocytic and frequently granulomatous inflammation of the peripheral airways, alveoli, and surrounding interstitial tissue which...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2017-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/23995 |
| _version_ | 1811301483827691520 |
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| author | Mariana Mukchailivna Fyrduchco – Regeda Zoryana Ljubomurivna Solvar Mariana Ljubomurivna Baida |
| author_facet | Mariana Mukchailivna Fyrduchco – Regeda Zoryana Ljubomurivna Solvar Mariana Ljubomurivna Baida |
| author_sort | Mariana Mukchailivna Fyrduchco – Regeda |
| collection | DOAJ |
| description |
Hypersensitivity pneumonitis is a potentially fatal immunological lung disease caused by occupational or environmental exposure to specific antigens and resulting from lymphocytic and frequently granulomatous inflammation of the peripheral airways, alveoli, and surrounding interstitial tissue which develops as the result of a non-IgE-mediated allergic reaction to a variety of organic materials or low molecular weight agents that are present in the workplace. The offending agents can be classified into six broad categories that include bacteria, fungi, animal proteins, plant proteins.The cornerstone of treatment is early removal from exposure to the eliciting antigen, although the disease may show an adverse outcome even after avoidance of exposure to the causal agent. The primary insults cause the greatest production of reative oxygen species, which contributes to oxidative damage by attacking all macromolecules, including lipids, proteins and nucleic acids, leading to defects in their physiological function.
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| first_indexed | 2024-04-13T07:09:40Z |
| format | Article |
| id | doaj.art-00b64339dcbb48489abd79918b06ac31 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-04-13T07:09:40Z |
| publishDate | 2017-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-00b64339dcbb48489abd79918b06ac312022-12-22T02:56:53ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-02-0172Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolinMariana Mukchailivna Fyrduchco – Regeda0Zoryana Ljubomurivna Solvar1Mariana Ljubomurivna Baida2Danylo Halytsky Lviv National Medical UniversityDanylo Halytsky Lviv National Medical UniversityDanylo Halytsky Lviv National Medical University Hypersensitivity pneumonitis is a potentially fatal immunological lung disease caused by occupational or environmental exposure to specific antigens and resulting from lymphocytic and frequently granulomatous inflammation of the peripheral airways, alveoli, and surrounding interstitial tissue which develops as the result of a non-IgE-mediated allergic reaction to a variety of organic materials or low molecular weight agents that are present in the workplace. The offending agents can be classified into six broad categories that include bacteria, fungi, animal proteins, plant proteins.The cornerstone of treatment is early removal from exposure to the eliciting antigen, although the disease may show an adverse outcome even after avoidance of exposure to the causal agent. The primary insults cause the greatest production of reative oxygen species, which contributes to oxidative damage by attacking all macromolecules, including lipids, proteins and nucleic acids, leading to defects in their physiological function. https://apcz.umk.pl/JEHS/article/view/23995experimental allergic alveolitisfree radicalssuperoxyde dismutasethiotriazolin. |
| spellingShingle | Mariana Mukchailivna Fyrduchco – Regeda Zoryana Ljubomurivna Solvar Mariana Ljubomurivna Baida Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin Journal of Education, Health and Sport experimental allergic alveolitis free radicals superoxyde dismutase thiotriazolin. |
| title | Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| title_full | Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| title_fullStr | Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| title_full_unstemmed | Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| title_short | Biomarkers of pro- and antioxidant systems in guinea pigs’ blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| title_sort | biomarkers of pro and antioxidant systems in guinea pigs blood in late periods of experimental allergic alveolitis development and their correction with thiotriazolin |
| topic | experimental allergic alveolitis free radicals superoxyde dismutase thiotriazolin. |
| url | https://apcz.umk.pl/JEHS/article/view/23995 |
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