Cellular Markers of Active Disease and Cure in Different Forms of Leishmania infantum-Induced Disease

Cellular Markers of Active Disease and Cure in Different Forms of Leishmania infantum-Induced Disease

Increased numbers of peripheral blood mononucleocytes (PBMC) and increased IFN-γ secretion following in vitro challenge of blood samples with soluble Leishmania antigen (SLA), have been proposed as biomarkers of specific cell-mediated immunity, indicating that treatment of visceral leishmaniasis (VL...

Full description

Bibliographic Details
Main Authors:	Laura Botana, Belén Matía, Juan V. San Martin, Alberto Romero-Maté, Alicia Castro, Laura Molina, Laura Fernandez, Ana Ibarra-Meneses, Marta Aguado, Carmen Sánchez, Luis Horrillo, Carmen Chicharro, Javier Nieto, Sheila Ortega, José Manuel Ruiz-Giardin, Eugenia Carrillo, Javier Moreno
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-11-01
Series:	Frontiers in Cellular and Infection Microbiology
Subjects:	visceral leishmaniasis cutaneous leishmaniasis lymphadenopathic leishmaniasis mucosal leishmaniasis biomarker cure
Online Access:	https://www.frontiersin.org/article/10.3389/fcimb.2018.00381/full

Similar Items

Licochalcone a Exhibits Leishmanicidal Activity in vitro and in Experimental Model of Leishmania (Leishmania) Infantum
by: Julia M. Souza, et al.
Published: (2020-12-01)

Visceral and mucosal leishmaniasis mimicking Wilson disease and oral neoplasia
by: Carlo Bova, et al.
Published: (2022-01-01)

Therapeutic success and failure in using miltefosine to treat dogs naturally infected with Leishmania infantum
by: Gustavo Gonçalves, et al.
Published: (2024-02-01)

Canine visceral leishmaniasis in area with recent Leishmania transmission: prevalence, diagnosis, and molecular identification of the infecting species
by: Josiane Valadão Lopes, et al.
Published: (2020-09-01)

Place of Serology in the Diagnosis of Zoonotic Leishmaniases With a Focus on Visceral Leishmaniasis Due to Leishmania infantum
by: Maude F. Lévêque, et al.
Published: (2020-02-01)

Loop-Mediated Isothermal Amplification Allows Rapid, Simple and Accurate Molecular Diagnosis of Human Cutaneous and Visceral Leishmaniasis Caused by <i>Leishmania infantum</i> When Compared to PCR
by: Ana Victoria Ibarra-Meneses, et al.
Published: (2021-03-01)

Studies in the mouse model identify strain variability as a major determinant of disease outcome in Leishmania infantum infection
by: Filipe Marques, et al.
Published: (2015-12-01)

Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy
by: Gilles Darcis, et al.
Published: (2017-07-01)

Leishmania tropica infection in wild and domestic canines
by: G Baneth, et al.
Published: (2014-04-01)

A rare case of lingual mucosal leishmaniasis caused by reactivation of Leishmania infantum infection
by: Yannik Eggers, et al.
Published: (2025-02-01)

Bionomic aspects of Lutzomyia evansi and Lutzomyia longipalpis, proven vectors of Leishmania infantum in an endemic area of non-ulcerative cutaneous leishmaniasis in Honduras
by: Ángel Mejía, et al.
Published: (2018-01-01)

Tegumentary leishmaniasis mimicking visceralization in a cirrhotic patient: atypical cutaneous lesions and local immunological features
by: Sebastian Vernal, et al.
Published: (2020-01-01)

PF-429242, a Subtilisin Inhibitor, Is Effective in vitro Against Leishmania infantum
by: Patrícia de Almeida Machado, et al.
Published: (2021-01-01)

A Review of the Progress in the Development of Leishmaniasis Vaccines
by: Narges Khaghanzadeh, et al.
Published: (2024-07-01)

Rapid Clinical Management of Leishmaniasis in Emergency Department: A Case Report with Clinical Review of Recent Literature
by: Andrea Piccioni, et al.
Published: (2020-10-01)

Impact of leishmaniasis on public health
by: L. B Camargo, et al.
Published: (2006-01-01)

Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon
by: Rana El Hajj, et al.
Published: (2018-05-01)

Leishmania martiniquensis is a New Causative Agent for Cutaneous and Visceral Leishmaniasis in Humans
by: S. B. Chuelov, et al.
Published: (2018-12-01)

Vaccines for canine leishmaniasis
by: Clarisa B. Palatnik-De-Sousa
Published: (2012-04-01)

Evaluation of fluorimetry and direct visualization to interpret results of a loop-mediated isothermal amplification kit to detect Leishmania DNA
by: Ana V. Ibarra-Meneses, et al.
Published: (2018-04-01)

Clinical aspects of visceral leishmaniasis caused by L. infantum in adults. Ten years of experience of the largest outbreak in Europe: what have we learned?
by: Luis Horrillo, et al.
Published: (2019-07-01)

F1 Domain of the Leishmania (Leishmania) donovani Nucleoside Hydrolase Promotes a Th1 Response in Leishmania (Leishmania) infantum Cured Patients and in Asymptomatic Individuals Living in an Endemic Area of Leishmaniasis
by: Eugenia Carrillo, et al.
Published: (2017-07-01)

Successful use of a defined antigen/GM-CSF adjuvant vaccine to treat mucosal leishmaniasis refractory to antimony: a case report
by: Badaro Roberto, et al.
Published: (2001-01-01)

Successful use of a defined antigen/GM-CSF adjuvant vaccine to treat mucosal leishmaniasis refractory to antimony: a case report
by: Roberto Badaro, et al.

Comparison of real-time PCR and conventional PCR for detection of Leishmania (Leishmania) infantum infection: a mini-review
by: M Paiva-Cavalcanti, et al.
Published: (2010-01-01)

THE SERO-CONVERSION AND EVALUATION OF RENAL ALTERATIONS IN DOGS INFECTED BY Leishmania (Infantum) chagasi
by: Georgia Brenda Barros Alves, et al.
Published: (2013-04-01)

Serological cross-reactivity of Trypanosoma cruzi, Ehrlichia canis, Toxoplasma gondii, Neospora caninum and Babesia canis to Leishmania infantum chagasi tests in dogs
by: Maurício Franco Zanette, et al.
Published: (2014-01-01)

Unusual Observations in Leishmaniasis—An Overview
by: Priya Yadav, et al.
Published: (2023-02-01)

Leishmania infantum and Human Visceral Leishmaniasis, Argentina
by: Alejandra Barrio, et al.
Published: (2012-02-01)

Effects of Visceralising Leishmania on the Spleen, Liver, and Bone Marrow: A Pathophysiological Perspective
by: Aikaterini Poulaki, et al.
Published: (2021-04-01)

Mucosal Leishmaniasis in Travelers with Leishmania braziliensis Complex Returning to Israel
by: Michal Solomon, et al.
Published: (2019-04-01)

Leishmania infantum detection in Nyssomyia neivai and dogs in Southern Brazil
by: Sabrina Fernandes Cardoso, et al.
Published: (2024-06-01)

Autochthonous Leishmania infantum in Dogs, Zambia, 2021
by: David Squarre, et al.
Published: (2022-04-01)

Elucidating the role played by bone marrow in visceral leishmaniasis
by: Patricia Sampaio Tavares Veras, et al.
Published: (2023-10-01)

Painful and swollen tongue: mucosal leishmaniasis due to Leishmania infantum
by: Ga-Lai M Chong, et al.
Published: (2021-12-01)

Leishmaniasis Visceral Infantil: Reporte de Caso y Revisión de Literatura1
by: Ibrahim Clós Mahmud, et al.
Published: (2014-04-01)

Occurrence of two autochthonous cases of American cutaneous leishmaniasis in the neighborhood of Caju, city of Rio de Janeiro, Brazil
by: Fred Bernardes Filho, et al.
Published: (2014-09-01)

Clinical and Laboratory Analysis of Patients with Leishmaniasis: A Retrospective Study from a Tertiary Care Center in New Delhi
by: Nitin GUPTA, et al.
Published: (2017-12-01)

Cross-protective immunity to Leishmania amazonensis is mediated by CD4+ and CD8+-epitopes of Leishmania donovani Nucleoside Hydrolase terminal domains
by: Dirlei eNico, et al.
Published: (2014-05-01)

Predictive factors for Leishmania infantum infection in dogs examined at a veterinary teaching hospital in Teresina, State of Piauí, Brazil
by: Marcus Vinicius Gouvêa, et al.
Published: (2016-02-01)