An investigation of the association between focal damage and global network properties in cognitively impaired and cognitively preserved patients with multiple sclerosis

An investigation of the association between focal damage and global network properties in cognitively impaired and cognitively preserved patients with multiple sclerosis

IntroductionThe presence of focal cortical and white matter damage in patients with multiple sclerosis (pwMS) might lead to specific alterations in brain networks that are associated with cognitive impairment. We applied microstructure-weighted connectomes to investigate (i) the relationship between...

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Bibliographic Details
Main Authors: A. L. Wenger, Muhamed Barakovic, Sara Bosticardo, Sabine Schaedelin, Alessandro Daducci, Simona Schiavi, Matthias Weigel, Reza Rahmanzadeh, Po-Jui Lu, Alessandro Cagol, Ludwig Kappos, Jens Kuhle, Pasquale Calabrese, Cristina Granziera
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neuroscience
Subjects:
multiple sclerosis (MS)
connectomics
structural connectivity
neuropsychological test
information processing speed
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1007580/full

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