EFFECT OF ANTIHYPERTENSIVE THERAPY BASED ON NEW METHOD OF INDIVIDUAL CHOICE OF DRUGS ON LEFT VENTRICULAR HYPERTROPHY IN ELDERLY PATIENTS
<p><strong>Aim.</strong> To study the effects of antihypertensive therapy based on consideration of individual heart rhythm variability (HRV) on left ventricular hypertrophy (LVH) in hypertensive elderly patients.</p><p><strong>Material and methods.</strong>...
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| Format: | Article |
| Language: | English |
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Столичная издательская компания
2015-12-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | http://www.rpcardio.ru/jour/article/view/539 |
| Summary: | <p><strong>Aim.</strong> To study the effects of antihypertensive therapy based on consideration of individual heart rhythm variability (HRV) on left ventricular hypertrophy (LVH) in hypertensive elderly patients.</p><p><strong>Material and methods.</strong> 60 hypertensive elderly patients with LVH were included in the study. They were split in two groups (30 people in each one). Patients of the group-I had common antihypertensive therapy. Patients of group-II received medications prescribed with consideration of individual heart rate variability. Holter monitoring with analysis of HRV, 24-hour blood pressure monitoring and ultrasonography were conducted initially and 18 months after treatment beginning.</p><p><strong>Results.</strong> BP control was reached in the majority of patients of both groups. The patients of group-II in comparison with patients of group-I had reduction of low- high frequency power ratio (LF/HF) and higher rate of LVH reduction. Relationship between LVH dynamics and ratio LF/HF was found.</p><p><strong>Conclusion.</strong> Arterial hypertension therapy considering individual HRV contributes in LVH reduction in elderly patients.</p> |
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| ISSN: | 1819-6446 2225-3653 |