How Kinesin-1 Utilize the Energy of Nucleotide: The Conformational Changes and Mechanochemical Coupling in the Unidirectional Motion of Kinesin-1
Kinesin-1 is a typical motile molecular motor and the founding member of the kinesin family. The most significant feature in the unidirectional motion of kinesin-1 is its processivity. To realize the fast and processive movement on the microtubule lattice, kinesin-1 efficiently transforms the chemic...
Main Authors: | Jingyu Qin, Hui Zhang, Yizhao Geng, Qing Ji |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/18/6977 |
Similar Items
-
Neck linker docking is critical for Kinesin-1 force generation in cells but at a cost to motor speed and processivity
by: Breane G Budaitis, et al.
Published: (2019-05-01) -
Molecular Mechanism of Processive Stepping of Kinesin Motors
by: Ping Xie
Published: (2021-09-01) -
Effect of the Neck Linker on Processive Stepping of Kinesin Motor
by: Ping Xie
Published: (2023-01-01) -
Processivity of dimeric kinesin‐1 molecular motors
by: Si‐Kao Guo, et al.
Published: (2018-08-01) -
The mechanism of kinesin inhibition by kinesin-binding protein
by: Joseph Atherton, et al.
Published: (2020-11-01)