Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp
Purpose: To successfully plan and treat a patient with diffuse angiosarcoma involving the face and scalp with intensity-modulated proton therapy (IMPT) before surgical resection. Materials and Methods: A patient presented to the radiation oncology department for preoperative treatment of an angiosar...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2021-06-01
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| Series: | International Journal of Particle Therapy |
| Subjects: | |
| Online Access: | https://theijpt.org/doi/pdf/10.14338/IJPT-D-20-00048.1 |
| _version_ | 1827160662583803904 |
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| author | Ashley Hunzeker, MS, CMD Daniel W. Mundy, PhD Jiasen Ma, PhD Trey C. Mullikin, MD Robert L. Foote, MD |
| author_facet | Ashley Hunzeker, MS, CMD Daniel W. Mundy, PhD Jiasen Ma, PhD Trey C. Mullikin, MD Robert L. Foote, MD |
| author_sort | Ashley Hunzeker, MS, CMD |
| collection | DOAJ |
| description | Purpose: To successfully plan and treat a patient with diffuse angiosarcoma involving the face and scalp with intensity-modulated proton therapy (IMPT) before surgical resection.
Materials and Methods: A patient presented to the radiation oncology department for preoperative treatment of an angiosarcoma diffusely involving the face and scalp. A 4-field IMPT technique was used to create a homogeneous dose distribution to the entire target volume while sparing underlying critical structures from toxicity and low-dose spread. A custom Monte Carlo optimizer was necessary to achieve treatment goals. Biological dose was evaluated with a linear energy transfer–based biological enhancement model. Robustness criteria were evaluated per department standard. The patient was successfully planned and treated according to clinical goals.
Results: The patient successfully completed the course of IMPT and was able to undergo surgical resection. Pathology indicated no presence of angiosarcoma.
Conclusion: IMPT using a custom Monte Carlo optimizer is a suitable radiation therapy treatment option for patients with diffuse angiosarcoma of the scalp and face. |
| first_indexed | 2024-04-24T08:23:11Z |
| format | Article |
| id | doaj.art-00c2f71b18004ea29e81f8cb516c3853 |
| institution | Directory Open Access Journal |
| issn | 2331-5180 |
| language | English |
| last_indexed | 2025-03-21T00:16:35Z |
| publishDate | 2021-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Particle Therapy |
| spelling | doaj.art-00c2f71b18004ea29e81f8cb516c38532024-08-03T09:07:11ZengElsevierInternational Journal of Particle Therapy2331-51802021-06-018130431010.14338/IJPT-D-20-00048.1i2331-5180-8-1-304Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and ScalpAshley Hunzeker, MS, CMDDaniel W. Mundy, PhDJiasen Ma, PhDTrey C. Mullikin, MDRobert L. Foote, MDPurpose: To successfully plan and treat a patient with diffuse angiosarcoma involving the face and scalp with intensity-modulated proton therapy (IMPT) before surgical resection. Materials and Methods: A patient presented to the radiation oncology department for preoperative treatment of an angiosarcoma diffusely involving the face and scalp. A 4-field IMPT technique was used to create a homogeneous dose distribution to the entire target volume while sparing underlying critical structures from toxicity and low-dose spread. A custom Monte Carlo optimizer was necessary to achieve treatment goals. Biological dose was evaluated with a linear energy transfer–based biological enhancement model. Robustness criteria were evaluated per department standard. The patient was successfully planned and treated according to clinical goals. Results: The patient successfully completed the course of IMPT and was able to undergo surgical resection. Pathology indicated no presence of angiosarcoma. Conclusion: IMPT using a custom Monte Carlo optimizer is a suitable radiation therapy treatment option for patients with diffuse angiosarcoma of the scalp and face.https://theijpt.org/doi/pdf/10.14338/IJPT-D-20-00048.1total scalpintensity-modulated proton therapy (impt)angiosarcomamonte carlo (mc) |
| spellingShingle | Ashley Hunzeker, MS, CMD Daniel W. Mundy, PhD Jiasen Ma, PhD Trey C. Mullikin, MD Robert L. Foote, MD Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp International Journal of Particle Therapy total scalp intensity-modulated proton therapy (impt) angiosarcoma monte carlo (mc) |
| title | Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp |
| title_full | Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp |
| title_fullStr | Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp |
| title_full_unstemmed | Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp |
| title_short | Intensity-Modulated Proton Therapy (IMPT) Treatment of Angiosarcoma of the Face and Scalp |
| title_sort | intensity modulated proton therapy impt treatment of angiosarcoma of the face and scalp |
| topic | total scalp intensity-modulated proton therapy (impt) angiosarcoma monte carlo (mc) |
| url | https://theijpt.org/doi/pdf/10.14338/IJPT-D-20-00048.1 |
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