Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context
Summary: Background: The burden of heart failure (HF) is high globally, but information on its burden in the Eastern Mediterranean Region (EMR) is limited. This study provides a systematic analysis of the burden and underlying causes of HF in the EMR, including at the country level, between 1990 an...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | EClinicalMedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S258953702200517X |
| _version_ | 1797895519810355200 |
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| author | Razieh Hassannejad Davood Shafie Karam I. Turk-Adawi Ahmad Mohammad Hajaj Kamran Mehrabani-Zeinabad Michelle Lui Jacek A. Kopec Hanan F. Abdul Rahim Saeid Safiri Ibtihal Fadhil Wagida A. Anwar Ali H. Mokdad Sheikh Mohammed Shariful Islam Nizal Sarrafzadegan |
| author_facet | Razieh Hassannejad Davood Shafie Karam I. Turk-Adawi Ahmad Mohammad Hajaj Kamran Mehrabani-Zeinabad Michelle Lui Jacek A. Kopec Hanan F. Abdul Rahim Saeid Safiri Ibtihal Fadhil Wagida A. Anwar Ali H. Mokdad Sheikh Mohammed Shariful Islam Nizal Sarrafzadegan |
| author_sort | Razieh Hassannejad |
| collection | DOAJ |
| description | Summary: Background: The burden of heart failure (HF) is high globally, but information on its burden in the Eastern Mediterranean Region (EMR) is limited. This study provides a systematic analysis of the burden and underlying causes of HF in the EMR, including at the country level, between 1990 and 2019. Methods: We used the 2019 Global Burden of Disease (GBD) data for estimates of prevalence, years lived with disability (YLDs), and underlying causes of HF in the EMR. Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more), sex (male and female), and countries. Findings: In contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. Globally, the HF age-standardised prevalence and YLDs decreased by 7.06% (95% UI: −7.22%, −6.9%) and 6.82% (95% UI: −6.98%, −6.66%) respectively, from 1990 to 2019. The HF age-standardised prevalence and YLDs in the EMR in 2019 were 706.43 (95% UI: 558.22–887.87) and 63.46 (95% UI: 39.82–92.59) per 100,000 persons, representing an increase of 8.07% (95% UI: 7.9%, 8.24%) and 8.79% (95% UI: 8.61%, 8.97%) from 1990, respectively. Amongst EMR countries, the age-standardised prevalence and YLDs were highest in Kuwait, while Pakistan consistently had the lowest HF burden. The dramatic increase of the age-standardised prevalence and YLDs were seen in Oman (28.79%; 95% UI: 28.51%, 29.07% and 29.56%; 95% UI: 29.28%, 29.84%), while Bahrain witnessed a reduction over the period shown (−9.66%; 95% UI: −9.84%, −9.48% and−9.14%; 95% UI: −9.32%, −8.96%). There were significant country-specific differences in trends of HF burden from 1990 to 2019. Males had relatively higher rates than females in all age groups. Among all causes of HF in 2019, ischemic heart disease accounted for the highest age-standardised prevalence and YLDs, followed by hypertensive heart disease. Interpretation: The burden of HF in the EMR was higher than the global, with increasing age-standardised prevalence and YLDs in countries of the region. A more comprehensive approach is needed to prevent underlying causes and improve medical care to control the burden of HF in the region. Funding: None. |
| first_indexed | 2024-04-10T07:27:07Z |
| format | Article |
| id | doaj.art-00c3103c69954b4b833b71b864eddd81 |
| institution | Directory Open Access Journal |
| issn | 2589-5370 |
| language | English |
| last_indexed | 2024-04-10T07:27:07Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | EClinicalMedicine |
| spelling | doaj.art-00c3103c69954b4b833b71b864eddd812023-02-24T04:31:14ZengElsevierEClinicalMedicine2589-53702023-02-0156101788Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in contextRazieh Hassannejad0Davood Shafie1Karam I. Turk-Adawi2Ahmad Mohammad Hajaj3Kamran Mehrabani-Zeinabad4Michelle Lui5Jacek A. Kopec6Hanan F. Abdul Rahim7Saeid Safiri8Ibtihal Fadhil9Wagida A. Anwar10Ali H. Mokdad11Sheikh Mohammed Shariful Islam12Nizal Sarrafzadegan13Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranHeart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranDepartment of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, QatarQU Health Research and Graduate Studies, QU Health, Qatar University, Doha, QatarCardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, IranFaculty of Medicine, School of Population & Public Health, University of British Columbia, Vancouver, CanadaFaculty of Medicine, School of Population & Public Health, University of British Columbia, Vancouver, Canada; Arthritis Research Canada, Vancouver, CanadaDepartment of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, QatarResearch Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranEastern Mediterranean NCD Alliance, Dubai, United Arab EmiratesCommunity Medicine Department, Faculty of Medicine, Ain Shams University, Egypt; Armed Forces College of Medicine (AFCM), EgyptInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA; Department of Health Metrics Sciences, University of Washington, Seattle, USAInstitute for Physical Activity and Nutrition, Deakin University, Melbourne, Australia; Corresponding author. Institute for Physical Activity and Nutrition, Deakin University, 221 Burwood Highway, Burwood, Melbourne, 3125, Victoria, Australia.Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran; Faculty of Medicine, School of Population & Public Health, University of British Columbia, Vancouver, Canada; Corresponding author. Isfahan Cardiovascular Research Institute, WHO Collaborating Center in the EMR, Isfahan University of Medical Sciences, Shahid Rahmani Alley, Moshtagh 3rd St., Isfahan, 8136747969, Iran.Summary: Background: The burden of heart failure (HF) is high globally, but information on its burden in the Eastern Mediterranean Region (EMR) is limited. This study provides a systematic analysis of the burden and underlying causes of HF in the EMR, including at the country level, between 1990 and 2019. Methods: We used the 2019 Global Burden of Disease (GBD) data for estimates of prevalence, years lived with disability (YLDs), and underlying causes of HF in the EMR. Age-standardised prevalence, YLDs, and underlying causes of HF were compared by 5-year age groups (considering 15 years old and more), sex (male and female), and countries. Findings: In contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. Globally, the HF age-standardised prevalence and YLDs decreased by 7.06% (95% UI: −7.22%, −6.9%) and 6.82% (95% UI: −6.98%, −6.66%) respectively, from 1990 to 2019. The HF age-standardised prevalence and YLDs in the EMR in 2019 were 706.43 (95% UI: 558.22–887.87) and 63.46 (95% UI: 39.82–92.59) per 100,000 persons, representing an increase of 8.07% (95% UI: 7.9%, 8.24%) and 8.79% (95% UI: 8.61%, 8.97%) from 1990, respectively. Amongst EMR countries, the age-standardised prevalence and YLDs were highest in Kuwait, while Pakistan consistently had the lowest HF burden. The dramatic increase of the age-standardised prevalence and YLDs were seen in Oman (28.79%; 95% UI: 28.51%, 29.07% and 29.56%; 95% UI: 29.28%, 29.84%), while Bahrain witnessed a reduction over the period shown (−9.66%; 95% UI: −9.84%, −9.48% and−9.14%; 95% UI: −9.32%, −8.96%). There were significant country-specific differences in trends of HF burden from 1990 to 2019. Males had relatively higher rates than females in all age groups. Among all causes of HF in 2019, ischemic heart disease accounted for the highest age-standardised prevalence and YLDs, followed by hypertensive heart disease. Interpretation: The burden of HF in the EMR was higher than the global, with increasing age-standardised prevalence and YLDs in countries of the region. A more comprehensive approach is needed to prevent underlying causes and improve medical care to control the burden of HF in the region. Funding: None.http://www.sciencedirect.com/science/article/pii/S258953702200517XGlobal burden of diseaseHeart failurePrevalenceYear lived with disabilityIschemic heart diseaseHypertension |
| spellingShingle | Razieh Hassannejad Davood Shafie Karam I. Turk-Adawi Ahmad Mohammad Hajaj Kamran Mehrabani-Zeinabad Michelle Lui Jacek A. Kopec Hanan F. Abdul Rahim Saeid Safiri Ibtihal Fadhil Wagida A. Anwar Ali H. Mokdad Sheikh Mohammed Shariful Islam Nizal Sarrafzadegan Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context EClinicalMedicine Global burden of disease Heart failure Prevalence Year lived with disability Ischemic heart disease Hypertension |
| title | Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context |
| title_full | Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context |
| title_fullStr | Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context |
| title_full_unstemmed | Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context |
| title_short | Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019Research in context |
| title_sort | changes in the burden and underlying causes of heart failure in the eastern mediterranean region 1990 2019 an analysis of the global burden of disease study 2019research in context |
| topic | Global burden of disease Heart failure Prevalence Year lived with disability Ischemic heart disease Hypertension |
| url | http://www.sciencedirect.com/science/article/pii/S258953702200517X |
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