Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture

The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over 100 genes have been studied as candidates for TB susceptibility, and several variants were identified by genome-wide association studies (GWAS), but few replicate. We established the International Tubercul...

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Bibliographic Details
Main Authors: Haiko Schurz, Vivek Naranbhai, Tom A Yates, James J Gilchrist, Tom Parks, Peter J Dodd, Marlo Möller, Eileen G Hoal, Andrew P Morris, Adrian VS Hill, International Tuberculosis Host Genetics Consortium
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
tuberculosis
GWAS
multi-ancestry
meta-analysis
HLA
Online Access:https://elifesciences.org/articles/84394

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