Dectin-1-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy

Dectin-1-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy

ABSTRACT Aspergillus species cause pulmonary invasive aspergillosis resulting in nearly 100,000 deaths each year. Patients at the greatest risk of developing life-threatening aspergillosis have weakened immune systems and/or various lung disorders. Patients are treated with antifungals such as ampho...

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Bibliographic Details
Main Authors: Suresh Ambati, Aileen R. Ferarro, S. Earl Kang, Jianfeng Lin, Xiaorong Lin, Michelle Momany, Zachary A. Lewis, Richard B. Meagher
Format: Article
Language:English
Published: American Society for Microbiology 2019-02-01
Series:mSphere
Subjects:
Aspergillus fumigatus
amphotericin B
antifungal agents
aspergillosis
beta-glucans
cell wall
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00025-19

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