Intracellular Transposition of Mobile Genetic Elements Associated with the Colistin Resistance Gene mcr-1

Intracellular Transposition of Mobile Genetic Elements Associated with the Colistin Resistance Gene mcr-1

ABSTRACT Mobile colistin resistance (mcr) genes are often located on conjugative plasmids, where their association with insertion sequences enables intercellular and intracellular dissemination throughout bacterial replicons and populations. Multiple mcr genes have been discovered in every habitable...

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Bibliographic Details
Main Authors: Richard N. Goodman, Supathep Tansirichaiya, Michael S. M. Brouwer, Adam P. Roberts
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
entrapment vector
insertion sequence
target site
antimicrobial resistance
plasmid
ISApl1
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03278-22

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