Resveratrol Alleviates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice by Mediating PI3K/Akt/VEGFA Pathway

Resveratrol Alleviates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice by Mediating PI3K/Akt/VEGFA Pathway

Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon, and its incidence is on the rise worldwide. Resveratrol (RSV), a polyphenolic compound, was recently indicated to exert anti-inflammatory effects on UC. Consequently, the current study was conducted to investigate the...

Bibliografske podrobnosti
Main Authors:	Fang Zhu, Jujia Zheng, Fang Xu, Yiyuan Xi, Jun Chen, Xiangwei Xu
Format:	Article
Jezik:	English
Izdano:	Frontiers Media S.A. 2021-08-01
Serija:	Frontiers in Pharmacology
Teme:	resveratrol ulcerative colitis phosphoinositide 3-kinase protein kinase B vascular endothelial growth factor A
Online dostop:	https://www.frontiersin.org/articles/10.3389/fphar.2021.693982/full

Podobne knjige/članki

Erratum: Resveratrol Alleviates Dextran Sulfate Sodium-Induced Acute Ulcerative Colitis in Mice by Mediating PI3K/Akt/ VEGFA Pathway
od: Frontiers Production Office
Izdano: (2021-11-01)

Resveratrol against 6-OHDA-induced damage of PC12 cells via PI3K/Akt
od: Huang Nanqu, et al.
Izdano: (2021-04-01)

Benzyl Isothiocyanate and Resveratrol Synergistically Alleviate Dextran Sulfate Sodium-Induced Colitis in Mice
od: Jianan Liu, et al.
Izdano: (2024-07-01)

Reducing PDK1/Akt Activity: An Effective Therapeutic Target in the Treatment of Alzheimer’s Disease
od: Shaobin Yang, et al.
Izdano: (2022-05-01)

Resveratrol Exerts Anti-Osteoarthritic Effect by Inhibiting TLR4/NF-κB Signaling Pathway via the TLR4/Akt/FoxO1 Axis in IL-1β-Stimulated SW1353 Cells
od: Xu X, et al.
Izdano: (2020-05-01)

Phosphatidylinositolphosphate phosphatase activities and cancer
od: Simon A. Rudge, et al.
Izdano: (2016-02-01)

Glutamine relieves oxidative stress through PI3K/Akt signaling pathway in DSS-induced ulcerative colitis mice
od: Shuguang Yan, et al.
Izdano: (2020-09-01)

miR‐330 alleviates dextran sodium sulfate‐induced ulcerative colitis through targeting IRAK1 in rats
od: Qing Zhang, et al.
Izdano: (2021-06-01)

Class IA PI3K isoforms lead to differential signalling downstream of PKB/Akt
od: Catalak Yilmaz Hazal B., et al.
Izdano: (2023-12-01)

The Inhibitory Effect of Geraniol on CCL4-induced Hepatorenal Toxicity in Pregnant Mice through the PI3K/AKT Signaling Pathway
od: Sabah Ali Alzahrani, et al.
Izdano: (2024-01-01)

Coumarin Derivative N6 as a Novel anti-hantavirus Infection Agent Targeting AKT
od: Zhoupeng Li, et al.
Izdano: (2021-12-01)

PI3K inhibitors in thrombosis and cardiovascular disease
od: Tom N. Durrant, et al.
Izdano: (2020-01-01)

Icariin protects against sodium azide—induced neurotoxicity by activating the PI3K/Akt/GSK-3β signaling pathway
od: Ying Zhang, et al.
Izdano: (2020-04-01)

Anticancer Effect of Fucoidan on DU-145 Prostate Cancer Cells through Inhibition of PI3K/Akt and MAPK Pathway Expression
od: Gang-Sik Choo, et al.
Izdano: (2016-07-01)

Treating cancer with phosphatidylinositol-3-kinase inhibitors: increasing efficacy and overcoming resistance
od: Marcia N. Paddock, et al.
Izdano: (2019-04-01)

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
od: Imelda Mary McGonnell, et al.
Izdano: (2012-07-01)

Profile of Tofacitinib in the Treatment of Ulcerative Colitis: An Evidence-Based Review of Recent Data
od: Varyani F, et al.
Izdano: (2019-12-01)

PI3K inhibitor treatment ameliorates the glucocorticoid insensitivity of PBMCs in severe asthma
od: Jing Bi, et al.
Izdano: (2020-02-01)

Autophagy activation in breast cancer cells in vitro after the treatment with PI3K/AKT/mTOR inhibitors
od: D. D. Grigoreva, et al.
Izdano: (2022-12-01)

Gaudichaudione H Inhibits Inflammatory Responses in Macrophages and Dextran Sodium Sulfate-Induced Colitis in Mice
od: Yiwen Jiang, et al.
Izdano: (2020-01-01)

Phosphoinositide Signaling in Immune Cell Migration
od: Ruchi Kakar, et al.
Izdano: (2023-11-01)

Phosphoinositides in the kidney
od: Leopoldo Staiano, et al.
Izdano: (2019-02-01)

Solanum trilobatum leaf extract-derived silver nanoparticles downregulate the PI3K/AKT/mTOR signaling pathway and attenuate oral squamous cell carcinoma cell proliferation
od: Anuradha Ganesan, et al.
Izdano: (2024-04-01)

Transmembrane protein 176B regulates amino acid metabolism through the PI3K-Akt-mTOR signaling pathway and promotes gastric cancer progression
od: Jing Li, et al.
Izdano: (2024-03-01)

The role of autophagy regulated by the PI3K/AKT/mTOR pathway and innate lymphoid cells in eosinophilic chronic sinusitis with nasal polyps
od: Jin‐Jing Zhuo, et al.
Izdano: (2024-06-01)

Delivery of Active AKT1 to Human Cells
od: Tarana Siddika, et al.
Izdano: (2022-11-01)

Effect of CHKA gene silencing on biological behavior of glioma cell and its mechanism
od: HUANG Ling , ZOU Yourui , LI Zuoqi , MA Yue , GAO Xinyi , MA Hui
Izdano: (2021-11-01)

Graphene oxide exacerbates dextran sodium sulfate-induced colitis via ROS/AMPK/p53 signaling to mediate apoptosis
od: Siliang Liu, et al.
Izdano: (2021-03-01)

Effect of hydrogen-rich water on brain injury in rats with acute radiation based on PI3K/AKT/Caspase-9 signaling pathway
od: Yong WANG, et al.
Izdano: (2023-03-01)

Activated PI3 Kinase Delta Syndrome: From Genetics to Therapy
od: David Michalovich, et al.
Izdano: (2018-02-01)

ATF5 promotes malignant T cell survival through the PI3K/AKT/mTOR pathway in cutaneous T cell lymphoma
od: Mengzhou Cao, et al.
Izdano: (2023-12-01)

Calcium-Prolactin Secretion Coupling in Rat Pituitary Lactotrophs Is Controlled by PI4-Kinase Alpha
od: Marek Kučka, et al.
Izdano: (2021-12-01)

Evaluation of Lymphoproliferative Disease and Increased Risk of Lymphoma in Activated Phosphoinositide 3 Kinase Delta Syndrome: A Case Report With Discussion
od: Michele N. Pham, et al.
Izdano: (2018-12-01)

The Role of Primary Cilia-Associated Phosphoinositide Signaling in Development
od: Chuan Chen, et al.
Izdano: (2022-12-01)

Phosphatidylinositol Kinases and Phosphatases in Entamoeba histolytica
od: Kumiko Nakada-Tsukui, et al.
Izdano: (2019-06-01)

PI3Kγδ inhibition suppresses key disease features in a rat model of asthma
od: James W. Pinkerton, et al.
Izdano: (2024-04-01)

Editorial for the Research Topic "Targeting PI3K/mTOR signaling in cancer"
od: Alexandre eArcaro
Izdano: (2014-04-01)

PI3K/Akt/mTOR inhibitors in breast cancer
od: Joycelyn JX Lee, et al.
Izdano: (2015-12-01)

Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells
od: Zhou Bing-rong, et al.
Izdano: (2012-11-01)

Gochujang, a traditional Korean fermented food, protects through suppressed inflammatory pathways and histological structure disruption in dextran sodium sulfate (DSS)-induced colitis mice
od: Hak Yong Lee, et al.
Izdano: (2024-03-01)