Synthesis, structural characterizations, in vitro biological evaluation and computational investigations of pyrazole derivatives as potential antidiabetic and antioxidant agents

Synthesis, structural characterizations, in vitro biological evaluation and computational investigations of pyrazole derivatives as potential antidiabetic and antioxidant agents

Abstract In this study, a two pyrazole derivatives; 2-(5-methyl-1H-pyrazole-3-carbonyl)-N-phenylhydrazine-1-carboxamide (Pyz-1) and 4-amino-5-(5-methyl-1H-pyrazol-3-yl)-4H-1,2,4-triazole-3-thiol (Pyz-2) were synthesized and characterized by 13C-NMR, 1H-NMR, FT-IR, and mass spectrometry. A complete m...

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Bibliographic Details
Main Authors: Salma Mortada, Khalid Karrouchi, El Hadki Hamza, Afaf Oulmidi, Mashooq Ahamd Bhat, Hassane Mamad, Youssra Aalilou, Smaail Radi, M’hammed Ansar, Azlarab Masrar, My El Abbes Faouzi
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51290-6

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https://doi.org/10.1038/s41598-024-51290-6

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