Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis.

Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis.

Morbi-mortality in cystic fibrosis (CF) is mainly related to chronic lung infection and inflammation, uncontrolled tissue rearrangements and fibrosis, and yet the underlying mechanisms remain largely unknown. We evaluated inflammatory and fibrosis responses to bleomycin in F508del homozygous and wil...

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Bibliographic Details
Main Authors: François Huaux, Sabrina Noel, Barbara Dhooghe, Nadtha Panin, Sandra Lo Re, Dominique Lison, Pierre Wallemacq, Etienne Marbaix, Bob J Scholte, Patrick Lebecque, Teresinha Leal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3667188?pdf=render

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http://europepmc.org/articles/PMC3667188?pdf=render

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