Infection in a rat model reactivates attenuated virulence after long-term axenic culture of Acanthamoeba spp

Infection in a rat model reactivates attenuated virulence after long-term axenic culture of Acanthamoeba spp

Prolonged culturing of many microorganisms leads to the loss of virulence and a reduction of their infective capacity. However, little is known about the changes in the pathogenic strains of Acanthamoeba after long culture periods. Our study evaluated the effect of prolonged culturing on the invasiv...

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Bibliographic Details
Main Authors: Carolina De Marco Verissimo, Vinicius Jose Maschio, Ana Paula Folmer Correa, Adriano Brandelli, Marilise Brittes Rott
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-11-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Acanthamoeba
virulence
in vivo
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000700832&lng=en&tlng=en

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